Development of Optimized Self-Nanoemulsifying Lyophilized Tablets to Improve Finasteride Clinical Pharmacokinetic Behavior

    November 2017 in “ Drug Development and Industrial Pharmacy ”
    Tarek Ahmed, Khalid M. El-Say, Khaled M. Hosny, Bader M Aljaeid
    Studysummary This study found that the optimized finasteride-loaded lyophilized tablets using a self-nanoemulsifying drug delivery system improved bioavailability in human volunteers compared to the marketed finasteride product.
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    Research cited in this study 5

    1. Transdermal Film-Loaded Finasteride Microplates to Enhance Drug Skin Permeation: Two-Step Optimization Study European Journal of Pharmaceutical Sciences · 2016
    2. Preparation of Finasteride Capsules-Loaded Drug Nanoparticles: Formulation, Optimization, In Vitro, and Pharmacokinetic Evaluation International Journal of Nanomedicine · 2016
    3. Finasteride Drugs · 1999
    4. Clinical Pharmacokinetics and Pharmacodynamics of Finasteride Clinical Pharmacokinectics · 1996
    5. Finasteride: A Slow-Binding 5-Alpha-Reductase Inhibitor Biochemistry · 1993

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