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Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Wnt ligands are crucial for hair growth and repair.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

About 2.2% of women with symptoms of high male hormones have a mild form of congenital adrenal hyperplasia, and measuring a specific hormone level can accurately diagnose it.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Aging causes skin stem cells to work less effectively.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Fat cells in the skin help start healing and form important repair cells after injury.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Women with PCOS are more likely to suffer from depression, anxiety, and stress.

The document concludes that rapid identification, isolation, and strict infection control are crucial to manage SARS outbreaks.

Hair follicle regeneration needs special conditions and young cells.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.