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420-450 / 1000+ resultsresearch Skin-On-A-Chip Strategies For Human Hair Follicle Regeneration
research The Historical Studies Underpinning the Concept of Hair Follicle Neogenesis
research Cells, Growth Factors and Biomaterials Used in Tissue Engineering for Hair Follicles Regeneration
research Back to the Future: From Appendage Development Toward Future Human Hair Follicle Neogenesis
![Periodontal Ligament Stem Cells: Regenerative Potency in Periodontium](/images/research/c7f827ba-6399-44e5-b97e-2d108a1487d8/small/19339.jpg)
research Periodontal Ligament Stem Cells: Regenerative Potency in Periodontium
Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.
research Using WGCNA to Identify Hub Genes of Skin Hair Follicle Development in Fetal Stage of Inner Mongolia Cashmere Goat
Researchers found WNT10A to be a key gene in developing goat hair follicles.
![Transient Stimulation of TRPMLs Enhances the Functionality of HDPCs and Facilitates Hair Growth in Mice](/images/research/2c03df51-24da-4c1a-a11a-748afde9a875/small/26855.jpg)
research Transient Stimulation of TRPMLs Enhances the Functionality of HDPCs and Facilitates Hair Growth in Mice
Activating TRPMLs helps human cells important for hair growth and increases hair growth in mice.
![Comparative Spatial Transcriptomic and Single-Cell Analyses of Human Nail Units and Hair Follicles Show Transcriptional Similarities between the Onychodermis and Follicular Dermal Papilla](/images/research/4d685c66-ead1-4b11-9ae5-fa2d54d0a61c/small/30460.jpg)
research Comparative Spatial Transcriptomic and Single-Cell Analyses of Human Nail Units and Hair Follicles Show Transcriptional Similarities between the Onychodermis and Follicular Dermal Papilla
Human nails and hair follicles have similar gene activity, especially in the cells that contribute to their growth and development.
![Direct Reprogramming of Mouse Fibroblasts into Dermal Papilla Cells via Small Molecules](/images/research/35e97991-b167-4def-805d-745851e85df0/small/19193.jpg)
research Direct Reprogramming of Mouse Fibroblasts into Dermal Papilla Cells via Small Molecules
Scientists turned mouse skin cells into hair-inducing cells using chemicals, which could help treat hair loss.
![Mediator 1 Ablation Induces Enamel-to-Hair Lineage Conversion in Mice Through Enhancer Dynamics](/images/research/94a56feb-8ada-44cf-807a-f85be2e0c7e6/small/19072.jpg)
research Mediator 1 Ablation Induces Enamel-to-Hair Lineage Conversion in Mice Through Enhancer Dynamics
Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.
![Epidermal-Dermal Coupled Spheroids Are Important for Tissue Pattern Regeneration in Reconstituted Skin Explant Cultures](/images/research/84c7dd14-ca3a-4d7c-a48e-1f902b64d68c/small/34293.jpg)
research Epidermal-Dermal Coupled Spheroids Are Important for Tissue Pattern Regeneration in Reconstituted Skin Explant Cultures
Skin spheroids with both outer and inner layers are key for regrowing skin patterns and hair.
![Deficiency of the Human Cysteine Protease Inhibitor Cystatin M/E Causes Hypotrichosis and Dry Skin](/images/research/454114fb-0ba2-4da2-8cba-df1dcf32b324/small/34017.jpg)
research Deficiency of the Human Cysteine Protease Inhibitor Cystatin M/E Causes Hypotrichosis and Dry Skin
Not having enough cystatin M/E protein causes less hair growth and dry skin.
![Centrosomes Are Required for the Normal Development of the Skin Epithelium](/images/research/24e8f578-8217-45cf-bc10-dcb86989d8a8/small/22966.jpg)
research Centrosomes Are Required for the Normal Development of the Skin Epithelium
Centrosomes are essential for healthy skin and hair growth, and their role is different from that of cilia.
![Targeted Deletion of Crif1 in Mouse Skin Epidermis Impairs Skin Homeostasis](/images/research/61712897-7eee-4389-a0dd-c69ccef3cd68/small/19541.jpg)
research Targeted Deletion of Crif1 in Mouse Skin Epidermis Impairs Skin Homeostasis
Removing the Crif1 gene in mouse skin disrupts skin balance and hair growth.
![Crosstalk Between Androgen and Wnt/β-Catenin Leads to Changes in Wool Density in FGF5-Knockout Sheep](/images/research/81a4efff-ef82-4986-9af6-241a1aae4491/small/17465.jpg)
research Crosstalk Between Androgen and Wnt/β-Catenin Leads to Changes in Wool Density in FGF5-Knockout Sheep
Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.
![Fibroblasts Become Fat to Reduce Scarring](/images/research/7b91f56f-50bc-44eb-8351-fca5c6b0a1b6/small/19566.jpg)
research Fibroblasts Become Fat to Reduce Scarring
Turning scar-forming cells into fat cells can reduce scarring.
![Mesenchymal Stem Cells for the Treatment of Skin Diseases](/images/research/2d523ebd-93c8-4cde-a715-0f7f21c6e2c6/small/13866.jpg)
research Mesenchymal Stem Cells for the Treatment of Skin Diseases
Mesenchymal stem cells show promise for treating various skin conditions and may help regenerate hair.
![Functional Skin Grafts: Where Biomaterials Meet Stem Cells](/images/research/48399ccc-2436-469f-809b-970ef3594bf8/small/19340.jpg)
research Functional Skin Grafts: Where Biomaterials Meet Stem Cells
Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
![Follistatin Promotes LIN28B-Mediated Supporting Cell Reprogramming and Hair Cell Regeneration in the Murine Cochlea](/images/research/215fe74c-c76e-455a-957d-5a2558542dbc/small/20548.jpg)
research Follistatin Promotes LIN28B-Mediated Supporting Cell Reprogramming and Hair Cell Regeneration in the Murine Cochlea
Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.
![Wharton's Jelly-Derived Mesenchymal Stem Cells in the Treatment of Four Patients with Alopecia Areata](/images/research/ad33d606-a980-4fe7-8821-fc3ff08870fe/small/13181.jpg)
research Wharton's Jelly-Derived Mesenchymal Stem Cells in the Treatment of Four Patients with Alopecia Areata
Wharton's jelly-derived stem cells were safely used to treat four alopecia patients, resulting in hair regrowth in all of them.
![Biology of Melanocytes in Mammals](/images/research/bd0763b1-1c73-44c1-946a-a251bc3cf2ad/small/35333.jpg)
research Biology of Melanocytes in Mammals
Melanocytes are important for skin and hair color and protect the skin from UV damage.
![Development and Prospects of Organ Replacement Regenerative Therapy](/images/research/af147c5d-f1e2-4ca5-8b22-b974fbc409d6/small/14462.jpg)
research Development and Prospects of Organ Replacement Regenerative Therapy
Scientists have made progress in creating replacement teeth, hair, and glands that work, which could lead to new treatments for missing teeth, baldness, and dryness conditions.
![Stem Cell Secretome as a Mechanism for Restoring Hair Loss Due to Stress, Particularly Alopecia Areata: Narrative Review](/images/research/d8afe2c4-ecf2-4742-9a35-ad04b0f46a57/small/13056.jpg)
research Stem Cell Secretome as a Mechanism for Restoring Hair Loss Due to Stress, Particularly Alopecia Areata: Narrative Review
Stem cells and their secretions could potentially treat stress-induced hair loss, but more human trials are needed.
![Safety and Efficacy of Leukocyte-Rich Platelet-Rich Plasma in the Treatment of Cicatricial Alopecia](/images/research/a3944a9f-721f-4bd1-a0f5-6ba76e13ca33/small/4875.jpg)
research Safety and Efficacy of Leukocyte-Rich Platelet-Rich Plasma in the Treatment of Cicatricial Alopecia
Leukocyte-rich platelet-rich plasma is safe and can potentially help treat scarring hair loss.
![Modulating the Stem Cell Niche for Tissue Regeneration](/images/research/72e0ffd3-8635-4ae7-8b4e-2567ba1da7b2/small/19726.jpg)
research Modulating the Stem Cell Niche for Tissue Regeneration
Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.
![Minoxidil-Loaded Hyaluronic Acid Dissolving Microneedles to Alleviate Hair Loss in an Alopecia Animal Model](/images/research/2f0376a5-cff6-42b2-84e3-7490d6d9ca7b/small/5576.jpg)
research Minoxidil-Loaded Hyaluronic Acid Dissolving Microneedles to Alleviate Hair Loss in an Alopecia Animal Model
Minoxidil-loaded hyaluronic acid microneedles can effectively increase hair growth and could be a promising treatment for hair loss.
![Study of Clinicohistopathological Correlation of Skin Adnexal Tumors](/images/research/b603afd2-b58f-45d2-8520-3d477f9fdbde/small/30525.jpg)
research Study of Clinicohistopathological Correlation of Skin Adnexal Tumors
Benign skin adnexal tumors are more common than malignant ones, with trichoepithelioma and chondroid syringoma being the most frequent types.
![Therapeutic Potential of Patient iPSC-Derived Melanocytes in Autologous Transplantation](/images/research/0d185663-da3b-48c1-8050-e96106f6b560/small/36035.jpg)
research Therapeutic Potential of Patient iPSC-Derived Melanocytes in Autologous Transplantation
Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.
![Targeting the Wnt Pathways for Therapies](/images/research/f85ab75a-1135-469a-9138-efaf1519bc30/small/18921.jpg)
research Targeting the Wnt Pathways for Therapies
Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.