TLDR Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
Stem cells, which can be embryonic or adult, have the potential to rejuvenate skin and restore hair by producing new skin cells through division and differentiation. Epidermal stem cells, located in niches such as the interfollicular epidermis and hair follicles, renew the epidermis, sebaceous glands, and hair follicles. Dermal stem cells, found in hair papillae and around pericytes, form various specialized dermal cells. The Wnt signaling pathway plays a crucial role in controlling stem cell fate. Stem cells may aid in wound healing, tissue repair, and the regeneration of aged skin, hair, nails, and mucous membranes.
Cited in this study
8 / 8 results
179 citations
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April 2012 in “Nature Communications” Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.
55 citations
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March 2012 in “Journal of Investigative Dermatology” Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.
128 citations
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December 2011 in “Development” Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.
260 citations
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June 2011 in “Cell” Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
20 citations
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May 2011 in “Burns” PL-FUT is an effective hair restoration method for burn victims with minimal scarring and high patient satisfaction.
62 citations
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August 2009 in “British Journal of Dermatology” Epidermal stem cells could lead to new treatments for skin and hair disorders.
1039 citations
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February 2009 in “Nature Reviews Molecular Cell Biology” Skin stem cells are crucial for maintaining and repairing the skin and hair, using a complex mix of signals to do so.
143 citations
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November 2008 in “Experimental gerontology” Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
August 2022 in “Journal of Investigative Dermatology” Lef1 is essential for normal skin, hair growth, and healing wounds in mice.
December 2017 in “Chin J Cell Stem Cell (Electronic Edition)” Hair follicle stem cells help skin wounds heal faster.
January 2017 Dermal stem cells help regenerate hair follicles and heal skin wounds.
October 2016 Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
