Scaffolds for Epithelial and Hair Follicle Regeneration

    January 2019 in “ Elsevier eBooks ”
    Herminio Torres, Hongjun Wang
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    TLDR Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.
    This document discusses the challenges of repairing full-thickness skin wounds and the use of tissue-engineered skin grafts, specifically electrospun matrices, for regenerating skin and hair follicles. The document explores the importance of the extracellular matrix (ECM) in influencing cell behavior and phenotype for skin and hair follicle regeneration. It also discusses the use of scaffolds made of PCL and collagen for epithelial and hair follicle regeneration. The method involves layer-by-layer assembly of the multilayer and multicell construct, with the selective placement of DP aggregates allowing for an esthetically pleasing arrangement of hair follicles.
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