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5-alpha reductase inhibitors, like finasteride and dutasteride, may cause depression, but more research is needed to understand why.

Autophagy changes the protein makeup of hair.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Cinnamic acid may help hair grow by activating oxytocin receptors.

Neurosteroids help regulate oxytocin levels, especially during stress and pregnancy, to protect against premature labor.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

PCOS may increase the risk of mental health issues like depression and anxiety.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.

Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Gilles de la Tourette syndrome is treatable, with behavioral therapy as a recommended first option and other treatments available for more severe cases.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

The review suggests new ways to classify ejaculation problems and recommends different treatments based on the type of issue.

Many pediatric epilepsy patients experience preventable severe adverse drug reactions, especially with certain medications and risk factors.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Valproate is a mood stabilizer for bipolar disorder but has side effects and risks, especially during pregnancy.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Mild exercise reduces pain in older rats through a brain chemical, while intense exercise reduces pain in all rats through a different pain-blocking process.

Microglia, the brain's immune cells, may contribute to Polycystic Ovary Syndrome (PCOS) by altering the female brain's structure and function, with kisspeptin neurons and GABA neurotransmitters also playing a role.

Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.

Group a wide range of chemicals, not just phthalates, for assessing risks to male reproductive health.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.

The symposium highlighted the skin's role in sensing itch, pain, touch, and pleasure, and discussed new research and techniques for understanding and treating these sensations.

Old drugs can be used for new treatments, saving time and money, but there are challenges like needing more evidence and legal concerns.