Gilles De La Tourette Syndrome – A Treatable Condition?

    August 2016 in “ Revue Neurologique
    Andreas Hartmann, Davide Martino, Tytus Murphy
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    TLDR Gilles de la Tourette syndrome is treatable, with behavioral therapy as a recommended first option and other treatments available for more severe cases.
    The document from August 1, 2016, reviews treatment options for Gilles de la Tourette syndrome (GTS), emphasizing the potential of behavioral therapy (BT) as a first-line treatment due to its efficacy and lack of pharmacological side effects. It also discusses pharmacotherapy, with a focus on antipsychotics like aripiprazole and emerging treatments like cannabis derivatives, while noting the need for caution due to potential side effects such as tardive dyskinesia. Deep brain stimulation (DBS) is considered for refractory cases, with a randomized controlled trial involving 13 patients showing some benefit, although there are safety concerns and a need for more research. The document concludes with optimism for the future of GTS treatment, despite the current lack of large, well-designed controlled studies.
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