August 2024 in “Pharmaceuticals” This study found that oral administration of solubilized sturgeon oil in mice promoted hair growth and positively influenced the gut microbiome associated with hair growth promotion.
The conclusion is that a more comprehensive and precise approach is needed for diagnosing PCOS to address its broader health risks.
January 2023 in “Iranian Journal of Pharmaceutical Research” This study concluded that S. hexaphylla extract may improve androgenetic alopecia by reducing 5α-reductase and androgen receptor levels, inhibiting apoptosis, and promoting keratinocyte proliferation in experimental models.
3 citations
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September 2011 in “Daehan miyong hakoeji” This study found that Dansam-Samultang promoted hair growth and increased follicle number and depth in C57BL/6 mice, with effects similar to those of minoxidil.
March 2024 in “Molecules/Molecules online/Molecules annual” This study optimized the extraction process of bear grease through enzymatic hydrolysis and found that it was rich in unsaturated fatty acids, enhancing its hair growth-promoting properties in mice compared to traditional methods.
January 2024 in “Journal of Cosmetic Dermatology” Microneedling combined with other treatments significantly improves hair growth in people with hair loss and is safe.
September 2011 in “대한미용학회지” This study found that Dansam-Samultang may promote hair growth and hair loss prevention in C57BL/6 mice, with notable improvements in hair follicle number, depth, and dermal thickness.
January 2007 in “Strait Pharmaceutical Journal” In this study, water-soluble minoxidil promoted hair growth and influenced the hair cycle in a C57BL/6 mouse alopecia model, particularly at a 1.5% concentration.
11 citations
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September 2012 in “Journal of animal physiology and animal nutrition” This study demonstrated that mink hair growth and pelt quality significantly depend on dietary protein levels and DL-methionine supplementation during the growing-furring period.
This study found that Nubian ibex have developed genetic adaptations in response to their desert environment, including enhanced skin barrier, DNA repair, viral response, and metabolism of toxic compounds.
June 2023 in “Skin Research and Technology” In this study, researchers used high-resolution MRI to distinguish anatomical differences in the scalp and hair follicles between tertiary androgenetic alopecia and severe alopecia areata, identifying subcutaneous tissue layer thickness as a key discriminative factor with high diagnostic value.
10 citations
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June 2005 in “Small ruminant research” This study found that melatonin combined with bromocryptine treatment in Spanish goats increased secondary hair follicle numbers and extended the cashmere growth phase during spring.
8 citations
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April 2023 in “Advanced materials” In this study, implantable vascularized engineered thrombi using autologous whole blood improved skin wound healing in rats by promoting robust microcapillary networks and accelerating healing processes.
January 2022 in “Wiadomości lekarskie (Warsaw Poland)” This study found that Methylsulfonylmethane significantly reduced hair loss and enhanced hair growth and follicle number in male mice, attributed to its antioxidant and anti-inflammatory properties.
183 citations
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January 2014 in “BioMed Research International” This study reported that AA-PRP injections significantly increased hair count and density in individuals with pattern hair loss compared to baseline, demonstrating their potential for enhancing hair growth.
24 citations
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February 2007 in “International Journal of Dermatology” This case report describes a 45-year-old Japanese woman with metastatic cervical cancer, including rare scalp metastases, who experienced severe scalp tenderness and patchy hair loss before her death.
77 citations
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March 2004 in “Human Reproduction” This study found that women with symptoms of oligomenorrhoea and/or hirsutism are more likely to have polycystic ovaries and less favorable biochemical and clinical markers compared to asymptomatic women.
April 2021 in “Han'gug miyong haghoeji/Journal of the Korean society of cosmetology” This study found that consuming raw cheonggukjang improved various measures of scalp hair condition in middle-aged women over a 12-week period.
2 citations
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July 2022 in “Stem cell research & therapy” This study found that a large number of pelage hair follicle mesenchymal stem cells can be efficiently isolated using two-step Ficoll Density Gradient Sedimentation, promoting hair growth by secreting exosomes in mice.
29 citations
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April 2002 in “Human Reproduction” This study found an association between total ovarian volume, pre-antral follicle number, total follicular volume, and some biochemical indices of PCOS, but not with ovarian stromal volume.
May 2018 in “Journal of Investigative Dermatology” Activating Wnt in skin cells controls the number of hair follicles by directing cell movement and fate.
8 citations
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October 2017 in “Dermatology practical & conceptual” This study found that a spermidine-based nutritional supplement increased the number of anagen phase hair follicles in healthy humans, suggesting potential benefits for hair loss conditions.
7 citations
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September 2020 in “Frontiers in Cell and Developmental Biology” This study found that recombinant murine IL-36α increased the number of regenerated hair follicles and accelerated wound healing in a mouse model of wound-induced hair follicle neogenesis.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that treating human skin explants with TPA increased the number of certain melanocyte phenotypes in the interfollicular epidermis, suggesting that this ex vivo model can effectively replicate human skin's pharmacologic responses for studying potential treatments.
September 2016 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that jujube seed oil significantly increased the number of hair follicles in BALB/c mice compared to controls, suggesting potential benefits for hair growth.
1 citations
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January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study developed a mouse model to mimic PHGDH gene copy number gain, finding that increased PHGDH expression leads to abnormal melanin production, which may offer insights into its role in melanoma.
September 2024 in “Meditsinskiy sovet = Medical Council” The study observed that in women, the number of hair follicles with an internal root sheath decreases with age in the parietal region, also hinting at a reduction in hair follicle and shaft width.
April 2026 in “Biosensors” In this study, red-light irradiation significantly increased hair follicle numbers and ATP levels in a mouse model, highlighting low-level laser therapy's potential to enhance hair regeneration and alter the skin metabolic microenvironment.
May 2021 in “Journal of Dermatology and Cosmetic” This study found that using low-power lasers on cryosurgery-induced wounds in rats can prevent hair follicle necrosis and increase hair follicle numbers, with the experimental group showing significantly more hair follicles than the control group across all time points studied.
29 citations
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March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” This study observed that isoproterenol directs hair-follicle-associated pluripotent stem cells to differentiate into cardiac muscle cells in large numbers, forming tissue sheets of beating heart muscle cells in culture.