Increased PHGDH Expression Uncouples Hair Follicle Cycle Progression and Promotes Inappropriate Melanin Accumulation
January 2018
in “
bioRxiv (Cold Spring Harbor Laboratory)
”
Research cited in this study
10 / 10 resultsresearch Characterization of a New, Inducible Transgenic Mouse Model with GFP Expression in Melanocytes and Their Precursors
research mTOR Signaling Promotes Stem Cell Activation via Counterbalancing BMP-Mediated Suppression During Hair Regeneration
mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.
research Hairy Tale of Signaling in Hair Follicle Development and Cycling
Hair growth and development are controlled by specific signaling pathways.
research The Human Hair Follicle, A Bistable Organ?
Human hair follicles switch between active and resting phases unpredictably.
research Scratching the Surface of Skin Development
The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
research The Follicular Automaton Model: Effect of Stochasticity and Synchronization of Hair Cycles
The model showed that randomness accurately describes individual hair growth cycles and that synchronization can cause large fluctuations not seen in humans.
research Do Hair Bulb Melanocytes Undergo Apoptosis During Hair Follicle Regression (Catagen)?
Hair follicle melanocytes die during hair regression.
research Melanogenesis Is Coupled to Murine Anagen: Toward New Concepts for the Role of Melanocytes and the Regulation of Melanogenesis in Hair Growth
Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.
research Melanogenesis Is Coupled to Murine Anagen: New Concepts for the Role of Melanocytes and Regulation of Melanogenesis in Hair Growth
Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.
research Growth of the Hair
Hair growth is cyclic and influenced mainly by local factors.
Related Research
2 / 2 results
research Melanocyte Stem Cells: A Melanocyte Reservoir in Hair Follicles for Hair and Skin Pigmentation
Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
research Functionally Distinct Melanocyte Populations Revealed by Reconstitution of Hair Follicles in Mice
Only skin melanocytes, not other types, can color hair in mice.