Stauntonia Hexaphylla Extract Ameliorates Androgenic Alopecia by Inhibiting Androgen Signaling in Testosterone-Induced Alopecia Mice

Finasteride microspheres help reduce hair loss for up to eight weeks with fewer side effects.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Androgens may block hair growth signals, targeting this could treat hair loss.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

Finasteride may cause sexual side effects like erectile dysfunction, but they are reversible and affect less than 2% of men.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride for hair loss may cause gynecomastia; doctors should inform patients.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

TGF-β1 from dermal papilla cells suppresses hair growth, and targeting it may help treat androgenetic alopecia.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Finasteride 1 mg/day for five years effectively improves hair growth and slows hair loss in men with male pattern baldness, and is safe for long-term use.

Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.

Finasteride safely and effectively treats male pattern hair loss, but may cause reversible sexual issues and harm male fetuses.