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    Did you mean Cyclin D1?
    Glossary Cyclin D1

    regulates cell cycle progression from G1 to S phase

    Cyclin D1, also known as CCND1, is a protein that plays a crucial role in regulating the cell cycle, specifically the transition from the G1 phase to the S phase, where DNA replication occurs. It acts as a regulatory subunit for certain enzymes called cyclin-dependent kinases (CDKs), and its overexpression is often associated with various types of cancer, as it can lead to uncontrolled cell proliferation.

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    Research 10 of 1000+

    1. Epidermal Growth Factor Induces Proliferation of Hair Follicle-Derived Mesenchymal Stem Cells Through Epidermal Growth Factor Receptor-Mediated Activation of ERK and AKT Signaling Pathways Associated with Upregulation of Cyclin D1 and Downregulation of p16 Stem Cells and Development · 2016 · 83 citations
    2. Fatigue, alopecia and stomatitis among patients with breast cancer receiving cyclin-dependent kinase 4 and 6 inhibitors: a systematic review and meta-analysis Expert Review of Anticancer Therapy · 2017 · 28 citations
    3. RhoA promotes epidermal stem cell proliferation via PKN1-cyclin D1 signaling PLoS ONE · 2017 · 21 citations
    4. Circ-Smad5 retards the G1/S transition of cell cycle via inhibiting the activity of wnt/lef/cyclind1 signaling in JB6 cells Genes & Diseases · 2020 · 10 citations
    5. Cyclin-dependent kinase inhibitors, p21waf1/cip1 and p27kip1, are expressed site- and hair cycle-dependently in rat hair follicles Journal of Dermatological Science · 2001 · 9 citations
    6. Drug repurposing of cyclin-dependent kinase inhibitors for neutrophilic acute respiratory distress syndrome and psoriasis Journal of Advanced Research · 2024 · 8 citations
    7. Safety assessment of cyclin-dependent kinase 4/6 inhibitors and comparison of time to adverse events PLoS ONE · 2025 · 2 citations
    8. Cyclin D3 deficiency inhibits skin tumor development, but does not affect normal keratinocyte proliferation Oncology Letters · 2017 · 2 citations
    9. Cyclin-Dependent Kinase 4/6 Inhibitors and Dermatologic Adverse Events: Results from the EADV Task Force “Dermatology for Cancer Patients” International Study Cancers · 2023 · 1 citations
    10. Cyclin‐dependent kinase 4 expression alters the number of keratinocyte stem cells in the mouse hair follicle Cell Biology International · 2022 · 1 citations
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