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    Glossary Cyclin-dependent kinase

    enzyme that regulates cell cycle progression by partnering with cyclins

    Cyclin-dependent kinases (CDKs) are a family of enzymes that play a crucial role in regulating the cell cycle, which is the process cells go through to divide and replicate. They work by partnering with proteins called cyclins to control the progression of cells through different phases of the cell cycle, ensuring that cells divide at the right time and maintain proper function.

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    1. Fatigue, alopecia and stomatitis among patients with breast cancer receiving cyclin-dependent kinase 4 and 6 inhibitors: a systematic review and meta-analysis Expert Review of Anticancer Therapy · 2017 · 28 citations
    2. Cyclin-dependent kinase inhibitors, p21waf1/cip1 and p27kip1, are expressed site- and hair cycle-dependently in rat hair follicles Journal of Dermatological Science · 2001 · 9 citations
    3. Drug repurposing of cyclin-dependent kinase inhibitors for neutrophilic acute respiratory distress syndrome and psoriasis Journal of Advanced Research · 2024 · 8 citations
    4. Safety assessment of cyclin-dependent kinase 4/6 inhibitors and comparison of time to adverse events PLoS ONE · 2025 · 2 citations
    5. Cyclin-Dependent Kinase 4/6 Inhibitors and Dermatologic Adverse Events: Results from the EADV Task Force “Dermatology for Cancer Patients” International Study Cancers · 2023 · 1 citations
    6. Cyclin‐dependent kinase 4 expression alters the number of keratinocyte stem cells in the mouse hair follicle Cell Biology International · 2022 · 1 citations
    7. Abstract 3889: Cyclin-dependent kinase 4 levels affect the number of hair follicle stem cells in mouse epidermis Cancer Research · 2010
    8. Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells. Molecular Endocrinology · 1994
    9. 085 Coordinate expressions of cyclin-dependent kinase inhibitors and high sulfur protein in human hair follicles Journal of Dermatological Science · 1996
    10. Effects of dihydrotestosterone on rat dermal papilla cells in vitro European Journal of Pharmacology · 2015 · 19 citations
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