Search
for

    Glossary Cyclin-dependent kinase

    enzyme that regulates cell cycle progression by partnering with cyclins

    Cyclin-dependent kinases (CDKs) are a family of enzymes that play a crucial role in regulating the cell cycle, which is the process cells go through to divide and replicate. They work by partnering with proteins called cyclins to control the progression of cells through different phases of the cell cycle, ensuring that cells divide at the right time and maintain proper function.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Fatigue, alopecia and stomatitis among patients with breast cancer receiving cyclin-dependent kinase 4 and 6 inhibitors: a systematic review and meta-analysis Expert Review of Anticancer Therapy · 2017 · 28 citations
    2. Cyclin-dependent kinase inhibitors, p21waf1/cip1 and p27kip1, are expressed site- and hair cycle-dependently in rat hair follicles Journal of Dermatological Science · 2001 · 9 citations
    3. Drug repurposing of cyclin-dependent kinase inhibitors for neutrophilic acute respiratory distress syndrome and psoriasis Journal of Advanced Research · 2024 · 8 citations
    4. Safety assessment of cyclin-dependent kinase 4/6 inhibitors and comparison of time to adverse events PLoS ONE · 2025 · 2 citations
    5. Cyclin-Dependent Kinase 4/6 Inhibitors and Dermatologic Adverse Events: Results from the EADV Task Force “Dermatology for Cancer Patients” International Study Cancers · 2023 · 1 citations
    6. Cyclin‐dependent kinase 4 expression alters the number of keratinocyte stem cells in the mouse hair follicle Cell Biology International · 2022 · 1 citations
    7. Abstract 3889: Cyclin-dependent kinase 4 levels affect the number of hair follicle stem cells in mouse epidermis Cancer Research · 2010
    8. Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells. Molecular Endocrinology · 1994
    9. 085 Coordinate expressions of cyclin-dependent kinase inhibitors and high sulfur protein in human hair follicles Journal of Dermatological Science · 1996
    10. Effects of dihydrotestosterone on rat dermal papilla cells in vitro European Journal of Pharmacology · 2015 · 19 citations
    11. Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues The Journal of Physiology · 2015 · 8 citations
    12. The Effect of EGR1 on the Proliferation of Dermal Papilla Cells Genes · 2022 · 5 citations
    13. Novel small molecules downregulate CDK1 expression and inhibit Wnt/β-catenin signaling in cutaneous squamous cell carcinoma by targeting its distinct tumor-specific cellular landscape Experimental & Molecular Medicine · 2025
    14. Poster Presentations at the 28th Joint Meeting of the International Society of Dermatopathology, March 5–6, 2025, Orlando, Florida, USA American Journal of Dermatopathology · 2025
    15. Understanding The Molecular Mechanisms Of Hair Follicle Stem Cell Quiescence And Genome Plasticity eCommons (Cornell University) · 2013
    16. The Critical Roles of Serum/Glucocorticoid-Regulated Kinase 3 (SGK3) in the Hair Follicle Morphogenesis and Homeostasis American Journal of Pathology · 2006 · 9 citations
    17. CPK1 activates CNGCs through phosphorylation for Ca2+ signaling to promote root hair growth in Arabidopsis Nature Communications · 2025
    18. CDK4/6 plus aromatase inhibitor-induced alopecia in breast cancer patients. Journal of Clinical Oncology · 2019 · 4 citations
    19. HIF‐2α/ARNT complex regulates hair development <i>via</i> induction of p21 <sup>Waf1/Cip1</sup> and p27 <sup>Kip1</sup> The FASEB Journal · 2014 · 4 citations
    20. <i>BUZZ</i>: an essential gene for postinitiation root hair growth and a mediator of root architecture in <i>Brachypodium distachyon</i> New phytologist · 2023
    21. Akt2 and SGK3 are both determinants of postnatal hair follicle development The FASEB Journal · 2009 · 24 citations
    22. 1272 p21Waf1/Cip1 is differentially expressed in epidermal versus follicular melanocytes and melanoma cells and is phenotypically regulated by UVB-mediated apoptosis 2023
    23. Overcoming the Low Bioavailability of Apigenin: The Therapeutic Efficacy for Androgenetic Alopecia Through Topical Administration Food Science & Nutrition · 2025
    24. Regulation of self-renewal in colorectal cancer cell models Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya) · 2014
    25. Keratin 17 modulates hair follicle cycling in a TN<i>Fα</i>-dependent fashion Genes & Development · 2006 · 169 citations
    26. Nuclear Factor I-C Regulates TGF-β-dependent Hair Follicle Cycling* Journal of Biological Chemistry · 2010 · 25 citations
    27. Cell Density-Dependent Upregulation of PDCD4 in Keratinocytes and Its Implications for Epidermal Homeostasis and Repair International Journal of Molecular Sciences · 2015 · 10 citations
    28. Phosphatidylinositol 3-Kinase/Akt-Dependent and -Independent Protection Against Apoptosis in Normal Human Melanocytes Journal of Investigative Dermatology · 2004 · 16 citations
    29. Lysocellin, a metabolite of the novel drug ‘alopestatin’, induces G1 arrest and prevents cytotoxicity induced by etoposide International Journal of Oncology · 2006 · 1 citations
    30. Wedelolactone, a medicinal plant-derived coumestan, induces caspase-dependent apoptosis in prostate cancer cells via downregulation of PKCε without inhibiting Akt International Journal of Oncology · 2012 · 83 citations