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Glossaryp15INK4b

protein that inhibits cell cycle progression to prevent uncontrolled division

p15INK4b, also known as CDKN2B, is a protein that helps regulate the cell cycle by inhibiting certain enzymes called cyclin-dependent kinases (CDKs). This inhibition prevents cells from dividing uncontrollably, which is crucial for preventing cancer. In the context of hair and alopecia, disruptions in the regulation of cell division can affect hair follicle function and growth.

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research Cellular Senescence in Tissue Repair: Every Cloud Has a Silver Lining

33 citations , January 2018 in “The International Journal of Developmental Biology”

Cell aging can be both good and bad for tissue repair.

research Epigenetic Control of Adult Stem Cell Function

179 citations , July 2016 in “Nature Reviews Molecular Cell Biology”

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

research Ginseng Phytochemicals as Therapeutics in Oncology: Recent Perspectives

50 citations , February 2018 in “Biomedicine & pharmacotherapy”

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

research Metabolic Pathways of Eicosanoids: Derivatives of Arachidonic Acid and Their Significance in Skin

January 2025 in “Cellular & Molecular Biology Letters”

Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.

research Follistatin Promotes LIN28B-Mediated Supporting Cell Reprogramming and Hair Cell Regeneration in the Murine Cochlea

16 citations , February 2022 in “Science Advances”

Follistatin and LIN28B together improve the ability of inner ear cells in mice to regenerate into hearing cells.

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