Search
for

    Glossary p15INK4b

    protein that inhibits cell cycle progression to prevent uncontrolled division

    p15INK4b, also known as CDKN2B, is a protein that helps regulate the cell cycle by inhibiting certain enzymes called cyclin-dependent kinases (CDKs). This inhibition prevents cells from dividing uncontrollably, which is crucial for preventing cancer. In the context of hair and alopecia, disruptions in the regulation of cell division can affect hair follicle function and growth.

    Sort by

    Research 18

    1. Comparison of allogeneic stem cell transplant conditioning regimens in AML, MDS and CLL General internal medicine and clinical innovations · 2018
    2. Epigenetic control of adult stem cell function Nature Reviews Molecular Cell Biology · 2016 · 179 citations
    3. Cellular senescence in tissue repair: every cloud has a silver lining The International Journal of Developmental Biology · 2018 · 33 citations
    4. The Role of Histone Demethylases in Disease Springer eBooks · 2011 · 1 citations
    5. Lysocellin, a metabolite of the novel drug ‘alopestatin’, induces G1 arrest and prevents cytotoxicity induced by etoposide International Journal of Oncology · 2006 · 1 citations
    6. Actinic Keratosis: Risk Factors, Clinical, Diagnosis and Therapeutics Aspects. Part I Dermatovenerologiâ, kosmetologiâ · 2024
    7. Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition Cell Cycle · 2006 · 295 citations
    8. From basic biology to engineered therapies: the keratinocyte stem cell playbook Frontiers in Medical Technology · 2026
    9. Epigenetics of Colorectal Cancer Gastroenterology · 2012 · 218 citations
    10. Evidence that Myc activation depletes the epidermal stem cell compartment by modulating adhesive interactions with the local microenvironment Development · 2003 · 182 citations
    11. p63 Regulates Human Keratinocyte Proliferation via MYC-regulated Gene Network and Differentiation Commitment through Cell Adhesion-related Gene Network Journal of Biological Chemistry · 2011 · 82 citations
    12. Miz1 is required for hair follicle structure and hair morphogenesis Journal of cell science · 2007 · 33 citations
    13. Oncogenic senescence: a multi-functional perspective Oncotarget · 2017 · 32 citations
    14. Changing Incidence Trends of Cutaneous B-Cell Lymphoma Journal of Investigative Dermatology · 2013 · 30 citations
    15. Follistatin promotes LIN28B-mediated supporting cell reprogramming and hair cell regeneration in the murine cochlea Science Advances · 2022 · 16 citations
    16. Long-term expansion of basal cells and the novel differentiation methods identify mechanisms for switching Claudin expression in normal epithelia Scientific Reports · 2025 · 1 citations
    17. Metabolic pathways of eicosanoids—derivatives of arachidonic acid and their significance in skin Cellular & Molecular Biology Letters · 2025
    18. Long-Term Effects of Sirolimus on Human Skin TSC2-Null Fibroblast‒Like Cells Journal of Investigative Dermatology · 2021 · 1 citations