141 citations
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November 2007 in “Journal of Investigative Dermatology” This study found that balding dermal papilla cells show premature senescence and altered expression of stress and DNA damage markers, suggesting sensitivity to environmental stress in androgenetic alopecia.
83 citations
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October 2016 in “Stem Cells and Development” This study found that epidermal growth factor significantly enhances the proliferation of hair follicle-derived mesenchymal stem cells through the EGFR/ERK and AKT pathways, without involving the STAT3 pathway.
58 citations
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May 2004 in “British Journal of Dermatology” This study found that topical immunotherapy affects angiogenesis and immune cell ratios in the scalp, potentially offering insights into the mechanisms underlying alopecia areata.
2 citations
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October 2017 in “Revista Da Associacao Medica Brasileira” The study found that silencing the gene p16INK4a in dermal papilla cells promotes their growth and aggregative behavior, suggesting a potential therapeutic target for androgenetic alopecia.
June 2026 in “British Journal of Dermatology” This study found that in men with androgenetic alopecia, a combination therapy of oral dutasteride and minoxidil was well tolerated and resulted in hair stabilization for nearly all participants by month 6, with 71.4% showing improvement by month 9.