Diagnostic Criteria for Polycystic Ovary Syndrome

    May 2017
    Francesco Orio, Giovanna Muscogiuri
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    TLDR The conclusion is that a more comprehensive and precise approach is needed for diagnosing PCOS to address its broader health risks.
    In 2017, Francesco Orio and Giovanna Muscogiuri reviewed the diagnostic criteria for Polycystic Ovary Syndrome (PCOS), highlighting the use of three main sets of criteria: the NIH, Rotterdam, and AE-PCOS Society criteria. They pointed out the confusion caused by the broadening of diagnostic criteria, which has led to the inclusion of multiple PCOS phenotypes in studies without proper stratification. The document also emphasized the need for a more comprehensive approach to diagnosing PCOS, considering its long-term health risks beyond fertility and cosmetic concerns. The Rotterdam criteria, which have broadened the definition of PCOS, are recommended for diagnosis. The authors called for the exclusion of other disorders in the diagnostic process, the use of new biomarkers, more objective methods for assessing hirsutism, and a clear differentiation between PCOS and PCOM. They suggested using follicle number per ovary (≥25) or ovarian volume for PCOM diagnosis and stressed the importance of further research to refine diagnostic criteria and prevent associated metabolic and cardiovascular diseases.
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