Nematic Fibrin Fibers Enabling Vascularized Thrombus Implants Facilitate Scarless Cutaneous Wound Healing
April 2023
in “
Advanced materials
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fibrin fibers vascularized thrombus implants cutaneous wound healing microcapillary vessel networks microfluidic shear stresses platelets endothelial cell maturation vascularization epidermis thickness collagen deposition hair follicle numbers neutrophil infiltration microvascular circulation M2 phenotype macrophages skin wound healing blood clot implants blood vessels skin thickness collagen hair follicles white blood cells blood flow macrophages
Studysummary In this study, implantable vascularized engineered thrombi using autologous whole blood improved skin wound healing in rats by promoting robust microcapillary networks and accelerating healing processes.
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