Inorganic-Based Biomaterials for Rapid Hemostasis and Wound Healing

    January 2023 in “ Chemical Science
    Zheng Yi, Jinfu Wu, Yufang Zhu, Chengtie Wu
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    TLDR Inorganic-based biomaterials can quickly stop bleeding and help wounds heal, but they may cause issues like sharp ion release and pH changes.
    The document reviews the development and application of inorganic-based biomaterials for rapid hemostasis (stopping bleeding) and wound healing. Various manufacturing techniques like 3D printing, freeze-drying, electrospinning, and vacuum filtration are used to create these biomaterials. They have unique advantages such as higher surface energy, making them hydrophilic and capable of quickly absorbing water for ultra-rapid hemostasis. They also possess various functions like bioactive ion release, photothermal properties, magnetothermal properties, photodynamic properties, or conductivity. The document also discusses the use of these biomaterials for wound healing and hair follicle regeneration. However, challenges such as the sharp release of ions and large pH changes from inorganic-based biomaterials, which can negatively affect tissue healing, are also highlighted. The document suggests that future research should focus on designing biomaterials that mimic native components and processes of hemostasis and wound healing.
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