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    Did you mean Epigenetic Regulation?
    Glossary Epigenetic Regulation

    chemical modifications that turn genes on or off

    Epigenetic Regulation refers to the process by which genes are turned on or off without changing the underlying DNA sequence. This is achieved through chemical modifications, such as DNA methylation and histone modification, which can influence gene expression and, consequently, cellular function. These changes can be influenced by environmental factors and can be heritable, playing a crucial role in development, disease, and adaptation.

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    1. Imprinted Dlk1-Gtl2 cluster miRNAs are potential epigenetic regulators of lamb fur quality BMC Genomics · 2023 · 1 citations
    2. Epigenetic regulations on skin wound healing: implications from current researches. PubMed · 2015 · 5 citations
    3. Identification of Epigenetic Regulator‐Associated Genes in Keloid Disease Through Integrated Bulk and Single‐Cell Transcriptomics With RT ‐ qPCR Validation The FASEB Journal · 2026
    4. Knockout of the ING5 epigenetic regulator confirms roles in stem cell maintenance and tumor suppression in vivo PLoS ONE · 2025
    5. INVESTIGATIONS INTO THE ROLE OF THE X-LINKED EPIGENETIC REGULATOR UTX (KDM6A) IN SELF-RENEWING STRATIFYING EPITHELIA Scholarly Commons (University of Pennsylvania) · 2025
    6. All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration Stem cell biology and regenerative medicine · 2018
    7. Hypoxia in Cell Reprogramming and the Epigenetic Regulations Frontiers in Cell and Developmental Biology · 2021 · 36 citations
    8. PROTACs in cancer therapy: targeted degradation of GPX4, PARP and epigenetic regulators Journal of Enzyme Inhibition and Medicinal Chemistry · 2026
    9. 0871 Skin longevity breakthroughs and targets for cellular age reversal: Sirtuins, key epigenetics regulators Journal of Investigative Dermatology · 2025
    10. Transcriptional and epigenetic mechanisms governing epidermal stem cell regulation Frontiers in Cell and Developmental Biology · 2026
    11. Identifying molecular targets for reverse aging using integrated network analysis of transcriptomic and epigenomic changes during aging Scientific Reports · 2021 · 12 citations
    12. Abnormal epigenetic modifications in peripheral blood mononuclear cells from patients with alopecia areata British Journal of Dermatology · 2011 · 48 citations
    13. Exploring the Drug Repurposing Versatility of Valproic Acid as a Multifunctional Regulator of Innate and Adaptive Immune Cells Journal of immunology research · 2019 · 47 citations
    14. Glucose metabolism regulates expression of hair-inductive genes of dermal papilla spheres via histone acetylation Scientific reports · 2020 · 6 citations
    15. Hairless and the polyamine putrescine form a negative regulatory loop in the epidermis Experimental Dermatology · 2013 · 10 citations
    16. Integrative Analysis of Methylome and Transcriptome Reveals the Regulatory Mechanisms of Hair Follicle Morphogenesis in Cashmere Goat Cells · 2020 · 24 citations
    17. Stepwise acquisition of unique epigenetic signatures during differentiation of tissue Treg cells Frontiers in Immunology · 2022 · 1 citations
    18. Sheep IGFBP2 and IGFBP4 promoter methylation regulates gene expression and hair follicle development Electronic Journal of Biotechnology · 2022 · 10 citations
    19. Integrated Analysis of Methylome and Transcriptome Changes Reveals the Underlying Regulatory Signatures Driving Curly Wool Transformation in Chinese Zhongwei Goats Frontiers in Genetics · 2020 · 39 citations
    20. 1435 Dynamic morphogen-p63 chromatin interactions that guide epigenetic changes and p63 activity in surface ectoderm commitment Journal of Investigative Dermatology · 2018
    21. Regulation of somatic cell reprogramming through inducible mir-302 expression Nucleic acids research · 2010 · 308 citations
    22. Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition Cell stem cell · 2016 · 174 citations
    23. UTX (KDM6A) promotes differentiation noncatalytically in somatic self-renewing epithelia Proceedings of the National Academy of Sciences · 2025
    24. Noval advance of histone modification in inflammatory skin diseases and related treatment methods Frontiers in immunology · 2024
    25. Prospects of alpha-ketoglutaric acid in the treatment of aging and age-related diseases 2025
    26. DEFINING THE ROLE OF ABI1 GENE IN PROSTATE CANCER PROGRESSION AND TREATMENT RESISTANCE Wiadomości Lekarskie · 2024
    27. Gelişmekte olan insan fetüslerinin ve yetişkinlerin derisinde EZH2 ekspresyonu: karşılaştırmalı bir çalışma 2023
    28. In Silico Promoter Motif Analysis of Human Fertility-Related Genes Applied Biosciences · 2026
    29. Molecular characterization, expression and methylation status analysis of BMP4 gene in skin tissue of Liaoning cashmere goat during hair follicle cycle Genetica · 2016 · 18 citations
    30. Alopecia areata − animal models Clinical and Experimental Dermatology · 2002 · 69 citations