Editorial Overview: Embroidering the Canvas of Life

The document from October 2018 provides an overview of significant advancements in genome engineering, cellular reprogramming, and tissue engineering. It discusses the creation of induced pluripotent stem cells (iPSCs), the use of transcription factors to direct cell fate, and the impact of epigenetic modifications on cell reprogramming. The editorial also highlights the use of organoids as models for studying human biology and genetics, the investigation of early human embryology, and the therapeutic possibilities of in vivo reprogramming. Furthermore, it raises ethical concerns regarding genome editing, especially in human embryos, underscoring the necessity for responsible use of these technologies and ongoing ethical discussions. The document underscores the critical need for continued research in these rapidly evolving scientific areas.