How a Bird Gets Its Feathers: Insights from Chromatin Looping
June 2020
in “
Developmental Cell
”
chromatin looping B-keratin genes enhancers Chr25 cluster Chr27 cluster epigenetic mechanisms skin appendage development skin heterogeneity gamma-tubulin ring complexes cryo-electron microscopy microtubule nucleation hair follicle regeneration B-keratin epigenetics skin development skin diversity gamma-tubulin cryo-EM microtubule formation hair regeneration
Studysummary This study observed that in chicken skin, large-scale differences in gene expression between feathered and scaly skin are controlled by enhancer-driven uniform expression, while small-scale differences within individual feathers are associated with chromatin looping.
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