Epidermal Stem Cells: An Update on Their Potential in Regenerative Medicine

    March 2013 in “ Expert opinion on biological therapy ”
    Xiaoyan Sun, Xiaobing Fu, Weidong Han, Min Zhao, Laura Chalmers
    Image of study
    TLDR Epidermal stem cells have potential for personalized regenerative medicine but need careful handling to avoid cancer.
    The document discussed the crucial role of adult epidermal stem cells in skin tissue regeneration and highlighted recent findings on their properties, functions, and potential in regenerative medicine. It noted that keratinocytes might have a transcriptional profile favorable for reprogramming, suggesting new strategies for patient-specific cell therapies. The paper provided an overview of the cells' differentiation and transdifferentiation capacities and their potential for tumorigenesis. The expert opinion emphasized the need for developing effective methods for lineage conversion between cell types and tailoring treatments to individual patients while minimizing cancer risks.
    Discuss this study in the Community →

    Research cited in this study

    9 / 9 results

    Related Community Posts Join

    6 / 54 results
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  44 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community Injecting stomach fat into the scalp could cure baldness in just six months

      in Update  114 upvotes 6 years ago
      A potential treatment for hair loss that involves injecting fat into the scalp; the role of testosterone and estrogen in thinning fat tissue under the skin; research on using lard to treat androgenic alopecia, as well as PRP + ACELL/amniotic stem cell treatments; and ongoing clinical trials by doctors involved in the study.

      community Keratin microspheres - breakthrough

      in Research/Science  13 upvotes 8 months ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

    Similar Research

    5 / 1000+ results