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    Glossary Embryonic Skin

    early developmental stage of skin in an embryo

    Embryonic skin refers to the early developmental stage of skin in an embryo, where the basic layers and structures of the skin begin to form. During this phase, the skin is highly proliferative and has the potential to differentiate into various cell types, including those that will eventually form hair follicles, sweat glands, and other specialized structures. This stage is crucial for understanding congenital skin disorders and the mechanisms of skin regeneration and repair.

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    1. Tissue-engineered dermal substitutes constructed by human embryonic stem cell-derived fibroblasts facilitate the repair of skin wounds Frontiers in Bioengineering and Biotechnology · 2026
    2. Stem cells in embryonic skin development Biological Research · 2012 · 43 citations
    3. Deciphering gene regulatory programs in mouse embryonic skin through single-cell multiomics analysis Genome biology · 2025
    4. Epidermal stem cells and skin tissue engineering in hair follicle regeneration World Journal of Stem Cells · 2015 · 83 citations
    5. Cellular Heterogeneity and Plasticity of Skin Epithelial Cells in Wound Healing and Tumorigenesis Stem cell reviews and reports · 2022 · 7 citations
    6. Functional Skin Grafts: Where Biomaterials Meet Stem Cells Stem Cells International · 2019 · 43 citations
    7. Therapeutic potential of stem cells in skin repair and regeneration Chinese Journal of Traumatology · 2008 · 73 citations
    8. Epidermal stem cell fate: what can we learn from embryonic stem cells? 2007 · 15 citations
    9. A human prenatal skin cell atlas reveals immune cell regulation of skin morphogenesis bioRxiv (Cold Spring Harbor Laboratory) · 2023
    10. Differention of ES cell-derived epidermal stem cells in full thickness skin defects Jiepouxue yanjiu · 2007
    11. Generation of human-induced pluripotent stem cell-derived adherent 3-dimensional skin hair-follicle organoids Organoid · 2022 · 2 citations
    12. Melanocytes in Human Embryonic and Fetal Skin: A Review and New Findings Pigment Cell Research · 1988 · 34 citations
    13. Wnt-10b secreted from lymphocytes promotes differentiation of skin epithelial cells Biochemical and Biophysical Research Communications · 2006 · 28 citations
    14. Embryonic NIPP1 depletion in keratinocytes triggers a cell-cycle arrest and premature senescence in adult mice Journal of Investigative Dermatology · 2024
    15. An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin Developmental cell · 2015 · 173 citations
    16. Expression of laminin, type IV collagen and fibronectin molecules is related to embryonal skin and epidermal appendage morphogenesis. PubMed · 2001 · 10 citations
    17. Transcriptional Characteristics Showed That miR-144-y/FOXO3 Participates in Embryonic Skin and Feather Follicle Development in Zhedong White Goose Animals · 2022 · 46 citations
    18. Faculty Opinions recommendation of Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2012
    19. EXPRESSION CHARACTERISTICS OF bFGF, EGF, TGF-β ISOFORMS AND THEIR RECEPTORS IN SKIN FROM FETUS AND ADULT Jiefangjun yixue zazhi · 2003
    20. Bioengineered skin organoids: from development to applications Military Medical Research · 2023
    21. Newly born mesenchymal cells disperse through a rapid mechanosensitive migration bioRxiv (Cold Spring Harbor Laboratory) · 2023
    22. Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development Frontiers in Cell and Developmental Biology · 2020 · 12 citations
    23. Function of KLF4 in Stem Cell Biology InTech eBooks · 2013 · 5 citations
    24. Stem Cells in Tissue Engineering Elsevier eBooks · 2014 · 3 citations
    25. 859 Building a functional niche for hair follicle stem cells Journal of Investigative Dermatology · 2017
    26. Transformation of amnion epithelium into skin and hair follicles Differentiation · 2004 · 33 citations
    27. Scratching the surface of skin development Nature · 2007 · 788 citations
    28. 231 Novel protocol for the invitro maintenance and expansion of adult epidermal LGR5+ stem cells Reproduction Fertility and Development · 2019
    29. Skin shedding and tissue regeneration in African spiny mice (Acomys) Nature · 2012 · 418 citations
    30. Functional and long-lived melanocytes from human pluripotent stem cells with transient ectopic expression of JMJD3 Stem Cell Research & Therapy · 2023 · 3 citations