Knockout of p16INK4a Promotes Aggregative Growth of Dermal Papilla Cells

October 2017 in “ Revista Da Associacao Medica Brasileira ”

Yi Cheng, Yang Gao, Lu Zhao, Shunqiang Gao, Guoqiang Zhang, Yan Zhang

p16INK4a dermal papilla cells hair follicle development hair growth androgenetic alopecia RNA interference cell cycle G1 phase S phase premature senescence DPCs AGA RNAi

Studysummary The study found that silencing the gene p16INK4a in dermal papilla cells promotes their growth and aggregative behavior, suggesting a potential therapeutic target for androgenetic alopecia.

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