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This review discusses the use of derma rollers for cosmetic purposes and their potential in transdermal drug delivery by summarizing evidence on their design, efficacy, safety, and concerns from preclinical and clinical reports.

This study found that finasteride microemulsions significantly increased skin permeability in vitro, highlighting the potential for enhanced delivery of this drug through the skin.

This study found that bovine lactoferrin promotes hair growth in mice by enhancing dermal papilla cell proliferation through the Erk/Akt and Wnt signaling pathways.

This study found that lncRNA-000133 may play a role in secondary hair follicle reconstruction and cashmere fiber growth in goats, potentially through its interaction with the methylation of its regulatory region and dermal papilla cells.

This study cataloged several long non-coding RNAs and microRNAs in cashmere goat dermal papilla cells, suggesting these non-coding RNAs may play a role in hair follicle stem cell activation and hair growth.

This study found that SFRP2 enhances Wnt3a-mediated β-catenin signaling in human dermal papilla cells, with higher SFRP2 expression in beard cells correlating with increased trichogenicity.

This study found that lipid nanocarriers called squarticles, conjugated with an antibody, enhanced minoxidil uptake in dermal papilla cells, potentially improving alopecia treatments.

This study found that osteopontin mRNA is abundantly expressed in dermal papilla cells during the catagen phase of hair growth in rats, suggesting a role in this phase.

This study found that 3D cultured hair follicle-like constructs, which include keratinocytes and dermal papilla cells, showed improved gene expression and cell interactions relevant to hair follicle development.

This study concluded that CD36-expressing dermal sheath cells may influence the modulation of blood capillaries in hair follicles, potentially affecting hair cycling.

This study found that injury affects the behavior of hair follicle dermal stem cells, steering them towards recruitment into the dermal papilla, a shift influenced by the hair cycle stage.

In this study, researchers established five new immortalized human dermal papilla cell lines from a male with androgenetic alopecia, which may serve as valuable tools for hair research.

This study found that mycophenolic acid promotes dermal papilla cell proliferation and anagen hair follicle induction in mice, suggesting potential as a treatment for hair-loss disorders.

This study suggests that red deer stags provide a novel model for investigating hormonal regulation of hair growth due to the different cell growth rates in hair follicles during breeding and nonbreeding seasons.

This study found that minoxidil sulfate and pinacidil did not activate K channel currents in hair follicles, suggesting their effect on hair growth might occur through other mechanisms like increased blood flow.

This study observed that injecting a combination of human cultured dermal papilla and epithelial cells induced hair growth in a mouse model.

This study found that human dermal papilla cells reprogram into induced pluripotent stem cells with higher efficiency than dermal fibroblasts, demonstrating their potential as an alternative source for iPS cells.

Niosomes are a promising and effective way to deliver drugs through the skin.

This study found that a newly developed hemi-vascularized sandwich method significantly improved the regeneration and maturity of hair follicles compared to other transplantation approaches in rat models.

This study found that CD90+ cells, resembling mesenchymal stem cells, are abundantly present in the lower part of anagen hair follicles in dogs.

In this study, Cyanidin 3-O-arabinoside was found to protect against DHT-induced dermal papilla cell senescence and mitochondrial dysfunction in androgenetic alopecia, restoring hair growth in mouse models.

This study observed that aging leads to significant structural and biological changes in the scalp's hair follicle environment in women, which may affect hair growth.

This study found that vanillic acid from wheat bran promoted dermal papilla cell proliferation, potentially stimulating hair growth by activating the PI3K/Akt and Wnt/β-catenin pathways.

This study suggests that the secretome from amniotic fluid-derived mesenchymal stem cells overexpressing Nanog could stimulate hair growth and increase follicle density, potentially aiding in alopecia treatment.

This laboratory study found that activated platelet‐rich plasma supernatant enhanced hair growth signaling pathways in cultured human dermal papilla cells, suggesting potential for treating androgenic alopecia.

This study suggests that co-culturing human outer root sheath cells with human dermal papilla cells can restore their ability to induce hair growth by altering gene expression through paracrine signaling.

This review discusses ethosomes as potential carriers for delivering drugs into deeper skin layers and provides no new clinical results, suggesting a need for further studies on their efficiency in dermal therapies.

This study suggests that interleukin-1 α influences dermal papilla cell activity by modifying androgen receptor expression and increasing the secretion of several growth factors and cytokines.

This study demonstrated that dermal papilla cells are molecularly distinct from fibroblasts and identified many novel molecules, including a new member of the CTGF protein family.

This study found that photobiomodulation enhanced hair regeneration in injured dermis of mice, likely through increased migration and exosome secretion of dermal papilla cells via the Akt/GSK-3β/β-catenin pathway.