Dermal Drug Delivery With Ethosomes: Therapeutic Potential

July 2007 in “ Therapy ”

Elka Touítou, Biana Godin

ethosomes minoxidil dermal therapy pilosebaceous structure acyclovir clindamycin cannabidiol erythromycin Rogaine

From the encyclopedia

An essential vasodilator with some anti-androgenic effects

Studysummary This review discusses ethosomes as potential carriers for delivering drugs into deeper skin layers and provides no new clinical results, suggesting a need for further studies on their efficiency in dermal therapies.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

Ethosomes, innovative carriers capable of overcoming the skin barrier, showed potential for delivering drugs into deeper skin layers, enhancing dermal therapy. The document reviewed the efficiency of ethosomal delivery systems containing drugs like acyclovir, clindamycin, minoxidil, cannabidiol, and erythromycin in both ex vivo and in vivo studies. These systems aimed to improve treatments for bacterial and viral skin infections, rheumatoid arthritis, and pilosebaceous structure-related disorders, potentially increasing drug-treatment efficiency and patient convenience.

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Research cited in this study

2 / 2 results

research Ethosomes: New Prospects in Transdermal Delivery

222 citations , January 2003 in “Critical Reviews in Therapeutic Drug Carrier Systems”

This review discusses the capabilities of ethosomes as drug delivery carriers and reports improved outcomes in a clinical study with an ethosomal acyclovir formulation.

research Enhanced Delivery of Drugs Into and Across the Skin by Ethosomal Carriers

182 citations , January 2000 in “Drug Development Research”

This study found that ethosomal carriers enhanced dermal and transdermal drug delivery more effectively than classic liposomes, improving delivery to deep skin layers and showing potential for treating conditions like herpes labialis and diabetes.