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    Glossary Dermal Adipocytes

    specialized skin cells that store fat and support hair growth

    Dermal adipocytes, also known as dermal fat cells, are specialized cells located in the dermis layer of the skin that store fat. These cells play a crucial role in maintaining skin structure, providing insulation, and aiding in wound healing. They also interact with hair follicles and can influence hair growth and regeneration.

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    1. Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair Cell Stem Cell · 2020 · 124 citations
    2. Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration Cell Reports · 2023 · 44 citations
    3. A guide to studying human dermal adipocytes in situ Experimental Dermatology · 2018 · 21 citations
    4. 477 Dietary fat- and obesity-sensitive dermal adipocyte PKCβ induction and inflammation cross-talk Journal of Investigative Dermatology · 2017
    5. Epidermal Wnt/beta-catenin signalling promotes dermal adipocyte differentiation during hair follicle morphogenesis and regeneration Journal of Dermatological Science · 2012
    6. 1339 Mature adipocytes inhibit the antimicrobial function of dermal adipogenic stem cells: An explanation for impaired cutaneous defense in obesity Journal of Investigative Dermatology · 2018
    7. The transcription elongation factors Spt4 and Spt6 promote dermal adipocyte differentiation Adipocyte · 2026
    8. Hair follicles’ transit-amplifying cells govern concurrent dermal adipocyte production through Sonic Hedgehog Genes & Development · 2016 · 75 citations
    9. PDGFA regulation of dermal adipocyte stem cells Stem cell investigation · 2017 · 3 citations
    10. 976 Knockout of mTOR/Akt inhibitor REDD1 results in hair cycle-independent dermal adipose expansion by promoting adipocyte differentiation Journal of Investigative Dermatology · 2019
    11. A review of adipocyte lineage cells and dermal papilla cells in hair follicle regeneration Journal of Tissue Engineering · 2014 · 35 citations
    12. Leptin of dermal adipose tissue is differentially expressed during the hair cycle and contributes to adipocyte‐mediated growth inhibition of anagen‐phase vibrissa hair Experimental Dermatology · 2014 · 30 citations
    13. Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice Journal of Clinical Investigation · 2019 · 136 citations
    14. Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis Cell Stem Cell · 2016 · 106 citations
    15. Adipocytes in Skin Health and Disease Cold Spring Harbor Perspectives in Medicine · 2014 · 77 citations
    16. The Role of Immature and Mature Adipocytes in Hair Cycling Trends in Endocrinology and Metabolism · 2018 · 30 citations
    17. TGFβ‐mediated inhibition of hypodermal adipocyte progenitor differentiation promotes wound‐induced skin fibrosis Cell Proliferation · 2024 · 3 citations
    18. Defining dermal adipose tissue Experimental Dermatology · 2014 · 218 citations
    19. Intradermal adipocytes mediate fibroblast recruitment during skin wound healing Development · 2013 · 238 citations
    20. Repeal and Replace: Adipocyte Regeneration in Wound Repair Cell Stem Cell · 2017 · 22 citations
    21. Rac-dependent signaling from keratinocytes promotes differentiation of intradermal white adipocytes bioRxiv (Cold Spring Harbor Laboratory) · 2018 · 1 citations
    22. 743 Adipocyte stem cells are maintained by Pdgfα signaling in the skin Journal of Investigative Dermatology · 2016
    23. Skin aging: are adipocytes the next target? Aging · 2016 · 70 citations
    24. Dermal White Adipose Tissue: A Newly Recognized Layer of Skin Innate Defense Journal of Investigative Dermatology · 2019 · 49 citations
    25. CXCL12+ dermal fibroblasts promote neutrophil recruitment and host defense by recognition of IL-17 The Journal of Experimental Medicine · 2024 · 32 citations
    26. Adipocyte-myofibroblast transition as a possible pathophysiological step in androgenetic alopecia Experimental Dermatology · 2017 · 18 citations
    27. DERMAL ADIPOSE TISSUE IN HAIR FOLLICLE CYCLING: POSSIBLE APPLICATIONS IN ALOPECIA? PubMed · 2017 · 2 citations
    28. Mast-cell driven dermal white adipose tissue remodeling amplifies inflammation and fibrosis in atopic dermatitis 2026
    29. Nelfb promotes dermal white adipose tissue formation through RNA Polymerase II mediated adipogenic gene regulation Development · 2025
    30. AB1159 HIGH FAT DIET AND THE ADIPOCYTE TO MYOFIBROBLAST TRANSITION: IMPLICATIONS FOR SYSTEMIC SCLEROSIS CUTANEOUS FIBROSIS 2024