Anti-Inflammatory Role of 15-Lipoxygenase Contributes to the Maintenance of Skin Integrity in Mice

    June 2018 in “ Scientific Reports ”
    Sang-Nam Kim, Seun Akindehin, Hyun-Jung Kwon … Yun Hee Lee
    Studysummary In this study, Alox15 knockout mice exhibited disrupted skin integrity and increased inflammation, suggesting that Alox15-mediated resolvin D2 production is crucial for maintaining skin homeostasis by suppressing inflammation.
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    Research cited in this study 4

    1. Regeneration of Fat Cells from Myofibroblasts During Wound Healing Science · 2017
    2. Dermal White Adipose Tissue: A New Component of the Thermogenic Response Journal of Lipid Research · 2015
    3. Mechanisms Regulating Skin Immunity and Inflammation Nature Reviews Immunology · 2014
    4. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011