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research Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice

29 citations , June 2018 in “Scientific Reports”

In this study, Alox15 knockout mice exhibited disrupted skin integrity and increased inflammation, suggesting that Alox15-mediated resolvin D2 production is crucial for maintaining skin homeostasis by suppressing inflammation.

research 878 Influence of bovine milk oligosaccharides on sebocyte lipid content and inflammatory mediators

April 2017 in “Journal of Investigative Dermatology”

In this study, bovine milk-derived oligosaccharides were found to increase sebocyte proliferation, lipid content, and inflammatory mediator synthesis through the mTORC1 pathway, potentially contributing to milk-based inflammation in sebocytes.

research Arachidonate 12-Lipoxygenase Inhibitors Promote S100A3 Citrullination in Cultured SW480 Cells and Isolated Hair Follicles

4 citations , January 2017 in “Biological & pharmaceutical bulletin”

This study found that inhibiting arachidonate 12-lipoxygenase (ALOX12) may enhance hair cuticle maturation by increasing S100A3 protein citrullination and promoting cuticular differentiation in isolated human hair follicles.

research Pharmacological and Phytochemical Updates on Citrullus colocynthis & Citrullus lanata

1 citations , January 2020 in “Indo global journal of pharmaceutical sciences”

This article reviews the traditional uses of Citrullus colocynthis for various conditions like cancer and jaundice but reports no new clinical results, underscoring its role in folk medicine.

research Alleviation of Mechanical Allodynia by 14,15-Epoxyeicosatrienoic Acid in a Central Poststroke Pain Model: Possible Role of Allopregnanolone and δ-Subunit-Containing Gamma-Aminobutyric Acid A Receptors

16 citations , November 2018 in “The journal of pain/Journal of pain”

This study found that in a rat model, 14,15-EET may alleviate central poststroke pain by enhancing thalamic inhibition through neurosteroid signaling, potentially outperforming gabapentin in early-stage treatment.

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community 15 months topical 5% min and 0.5 dut. Is this also regrowth? Or could these grow into terminal hairs at some point?

4 upvotes 3 weeks ago

The user has been using topical 5% minoxidil and 0.5 mg dutasteride for 15 months, noticing stronger hair and some new growth. They have experienced hair loss for 10 years, underwent two hair transplants, and are seeing density improvements, particularly in the frontal scalp.

community 15 months on finastride minoxidil

87 upvotes 1 month ago

After 15 months on finasteride (1mg every second day) and topical minoxidil, the user noticed new hair growth and fuller hair without side effects. The user is 29 years old and observed visible improvement after one year.

community 15 Months Ago vs 15 Minutes Ago (Fin + Min + Spiro + E)

43 upvotes 2 months ago

The user experienced significant hair regrowth using spironolactone, estradiol, minoxidil, and finasteride while transitioning. They noted reduced libido and increased grogginess as side effects.

community 15 years on Fin 1mg EoD- losing effectiveness- bad experience on min, ideas?

in Basic Questions 71 upvotes 5 months ago

The user has been using finasteride for 15 years but is noticing increased hair loss. They are considering increasing the finasteride dosage or switching to dutasteride but are concerned about side effects; they previously stopped using minoxidil due to heart palpitations.

community “15 week progress on aggressive protocol (dut + min + microneedling) — am I on track for transplant candidacy?

11 upvotes 6 months ago

The user has been using a hair loss treatment protocol including topical dutasteride, minoxidil with tretinoin, ketoconazole shampoo, microneedling, a laser cap, and vitamin D for 15 weeks, showing impressive progress. Feedback suggests continuing medical therapy for 12-24 months before considering a hair transplant.

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learn C 13-15 alkane

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Hair Transplant
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