A Direct Link Between Prss53, Hair Curvature, and Skeletal Dysplasia

    February 2019 in “ bioRxiv (Cold Spring Harbor Laboratory) ”
    Jichao Deng, Yuning Song, Liu H … Li Z

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This study found that Prss53-mutated rabbits exhibited curved hair and skeletal dyskinesia, suggesting a link between Prss53 loss and these traits, potentially involving disrupted calcium metabolism.
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    Research cited in this study 5

    1. Structural Changes of Hair Shaft After Application of Chemical Hair Straighteners: Clinical and Histopathological Study Journal of cosmetic dermatology · 2018
    2. Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome American journal of human genetics · 2016
    3. A Genome-Wide Association Scan in Admixed Latin Americans Identifies Loci Influencing Facial and Scalp Hair Features Nature Communications · 2016
    4. Hair Curvature: A Natural Dialectic and Review Biological reviews/Biological reviews of the Cambridge Philosophical Society · 2014
    5. Dermal Papilla Cell Number Specifies Hair Size, Shape, and Cycling, and Its Reduction Causes Follicular Decline Development · 2013

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