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Made 8 minoxidil samples; 1 cocrystal, 7 salts formed.

In this study, forming inclusion complexes of Finasteride and poly (ethylene glycol) resulted in significantly improved solubility and dissolution rates, suggesting a promising new solid form for enhanced drug release.

This study found that the new cocrystal formulation KET-PABA improved the antimycotic efficiency of ketoconazole and induced an anti-inflammatory response without causing skin sensitization in mice.

This case study found that a 7-year-old girl's crystalline cataract had sulfur-containing amino acids likely cystine, and was associated with abnormal hair conditions.

This study found that finasteride effectively prevented testosterone-induced kidney stone formation in renal tubular cells by reducing COM crystal adhesion and crystallization.

This article suggests that testosterone therapy might be considered if other treatments fail, but emphasizes discussing potential risks and benefits with patients before prescribing.

This study found that pretreatment with KP-Cryst fusion proteins effectively protected Asian and Caucasian virgin hair from thermal damage by maintaining higher water content and preventing structural changes during heat application.

This structural study reports on the crystal properties of a compound used for treating alopecia, revealing different conformations and nitrogen hybridization in its piperidine rings.

This study reports the crystal structure and geometric parameters of a modified Finasteride derivative, highlighting significant differences in dihedral angles compared to its solvated analog and computational models.

A new compound that could treat various androgen-related conditions was created and analyzed.

This article presents a case of spontaneous, recurrent necrotizing infundibular crystalline folliculitis in the inguinal region and suggests unknown etiology possibly linked to microbiome and sebaceous gland dysfunction.

This study investigated the effect of peracetic acid treatment on hair fiber structure and found that disulfide bond oxidation altered thermal properties while preserving the α-crystal structure, suggesting different stabilizing interactions in hair fibers.

A new compound was made that might help treat diseases related to male hormones.

This study reports that structural and biochemical analysis of steroid 5α-reductases clarifies how they mediate steroid reduction with NADPH, potentially aiding in designing targeted therapies.

This study determined the crystal structure and conformation of synthesized 17x-Acetoxy-pregn-4,6-diene-3,20-dione, revealing specific molecular interactions and structural details in an orthorhombic crystal system.

This study reports the crystal structure of C28H32O5, revealing its monoclinic symmetry, unit-cell dimensions, and molecular conformation.

The document concludes that a compound with potential for treating prostate cancer and hair loss was successfully made and its detailed structure was confirmed.

A new antiandrogen compound was made and its detailed three-dimensional shape was described.

This study suggests that finasteride-loaded liquid crystalline nanoparticles could be a viable alternative to oral administration for treating androgenetic alopecia due to their controlled release and skin permeation properties.

This study found that liquid crystalline nanoparticles formulated with Cremophor surfactants significantly enhanced skin permeation of finasteride compared to lower surfactant concentrations.

This study found that coating liquid crystalline nanoparticles with chitosan significantly enhanced the skin permeation of 5α-reductase inhibitors, suggesting a promising strategy for improving topical delivery in androgenetic alopecia treatment.

This study found that mu-crystallin gene expression in mouse skin is highest during the anagen phase of hair development, suggesting its possible role in hair follicle growth.

This study found that high levels of μ-crystallin in skeletal muscle are associated with greater fat metabolism and a shift in gene expression towards slower muscle function.

This study found that intracutaneous injections of nandrolone phenylpropionate specifically induced local epidermal thickening and increased sebaceous gland volume in female hairless hamsters, independent of a dermal inflammatory response.

This study found that the polyherbal gel formulations F4 and F6 demonstrated superior in vitro performance in hair care, showing promise as cosmeceutical candidates, although further in vivo and clinical studies are necessary to confirm their efficacy and safety.

Hair grows like a crystal at a solid-liquid interface without cell division.

This study found that the cocrystal of mycophenolic acid with isonicotinamide significantly improved solubility and dissolution rate, while two other cocrystals showed decreased performance in these areas.

This study characterized the crystal structures and supramolecular architectures of new salts made from 2,4-diaminopyrimidine and different dicarboxylic acids, revealing subtle differences in crystal packing and hydrogen-bonding patterns, particularly influenced by sulfur atom interactions, through Hirshfeld analysis and enrichment ratios.

This study found that surface-modified liquid crystalline nanoparticles significantly enhanced skin permeation of finasteride and dutasteride compared to unmodified nanoparticles, suggesting potential for improved treatment efficacy in androgenetic alopecia.