Development and In Vitro Evaluation of Liquid Crystal-Based Polyherbal Hair Gels: Physicochemical Characterization, Hair Performance, and Antioxidant Assessment

    Sheba R. David, Rajan Rajabalaya, Umi Haida Nadia Mohamed Jefri
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    Studysummary This study found that the polyherbal gel formulations F4 and F6 demonstrated superior in vitro performance in hair care, showing promise as cosmeceutical candidates, although further in vivo and clinical studies are necessary to confirm their efficacy and safety. Our plain-language summary of this paper — not a Tressless recommendation.
    The study developed liquid crystal-based polyherbal hair gels using herbal oils and extracts to improve hair care. Among 10 formulations, F6 showed optimal nanometric characteristics and stability, while F4 and F9 excelled in anti-frizz and anti-static properties. The gels enhanced hair thickness and exhibited moderate antioxidant activity. F4 and F6 remained stable over 28 days, suggesting their potential as cosmeceutical hair care products. However, further in vivo and clinical studies are necessary to confirm their efficacy and safety.
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