Development and Standardization of Poly Herbal Gel and Clinical Evaluation of Its Hair Growth Stimulation

The document summarizes a study on the development and clinical evaluation of a poly herbal gel designed to stimulate hair growth. Phytochemical studies were conducted on the plant powders and extracts of Lagenaria siceraria, Trichosanthis cucumarina, and Tridax procumbens to ensure quality and purity, and to identify active principles. The extracts showed significant amounts of flavonoids and phenolic compounds. The gel was formulated using water-soluble polymers and other agents to enhance scalp absorption. Standardization tests for the gel included assessments of viscosity, pH, homogeneity, spreadability, content uniformity, and skin irritation. The clinical evaluation involved human volunteers who applied the gel and were compared to a reference group using a gel without the extracts. Hair growth was measured using a trichoscope over 90 days. The study concluded that the poly herbal gel containing the extracts of the selected plants effectively stimulated hair growth.