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In this case report, a young woman experienced acute kidney injury linked to the use of a hair straightening product containing glyoxylic acid, suggesting dermal absorption may lead to calcium oxalate nephropathy; this highlights the need for regulatory review and public health intervention.

This review discusses current anti-inflammatory treatment options for calcium pyrophosphate crystal deposition disease (CPPD) and highlights the lack of crystal-targeted therapies, emphasizing the need for more research to guide treatment.

This study found that oxidative treatment with peracetic acid dissociates some disulfide bonds in human hair fibers while maintaining the crystalline structure, suggesting different mechanisms stabilize different regions of intermediate filaments.

The meeting showcased rare skin disease cases, highlighting the need for accurate diagnosis and treatment.

This study reported new crystallographic structures and polymorphs of finasteride, including several solvates with distinct X-ray diffraction patterns and thermally characterized properties.

This study observed that surfactants in cosmetic treatments can bind to keratinous tissues like hair and nails, affecting their tensile properties and possibly leading to deterioration depending on the specific detergents used.

This study found that supplementing young rats' diet with lactoflavin prevented cataract development, while a diet lacking all B vitamins, except flavin, led to cataracts and alopecia.

This study found that the loss of Msx2 in knockout mice led to phenotypes similar to Peters anomaly and microphthalmia, suggesting that MSX2 plays a critical role in anterior segment development of the eye.

Biotin deficiency in monkeys causes fur and skin issues, but 20 μg of biotin daily can prevent or cure it.

In this study, researchers developed a dissolvable microneedle patch containing baricitinib for alopecia areata treatment, reporting significantly higher hair growth in mouse models compared to controls, suggesting its potential as an effective, pain-free topical therapy.

In this study, combined treatment with transglutaminase and keratin significantly repaired damaged hair by improving its structural properties, reducing swelling, and enhancing crosslink activities, as evidenced by microscopy and spectroscopy analyses.

This study found that a bio-based repair solution containing hydrolysed wool keratin, serine, and transglutaminase improved the physical and chemical properties of damaged hair, increasing its strength, flexibility, and thermal stability while offering long-lasting protection against chemical damage.

In this study, the stability properties of various active pharmaceutical ingredients (APIs) were characterized, revealing how factors like pressure and water sensitivity influence their intrinsic stability and potential degradation.

This study found that, compared to oxidative treatments, reductive perm-waving more severely impacts the intermediate filaments in European human hair, while both treatments alter denaturation kinetics in a first-order manner.

This study found that freeze-dried finasteride nanoparticles significantly improved the dissolution rate and pharmacokinetic parameters compared to pure drug formulations, suggesting enhanced stability and solubility for poorly water-soluble drugs.

In this study, researchers addressed the limitations of adenosine's practical application in treating inflammation, oxidative stress, and tissue repair due to its poor water solubility and low transdermal permeability. Results are not reported in the abstract.

This study investigated the molecular mechanisms behind the formation of drug-polymer inclusion complexes and found that carbamazepine can self-assemble into stable channel structures without guest polymers, unlike griseofulvin, which requires guest molecules for structural stability.

This research elucidates the molecular mechanisms underlying carbamazepine and griseofulvin's inclusion complex channel formations with polymers, revealing why carbamazepine forms stable channels independently, while griseofulvin requires polymeric support due to weaker interactions.

Nanocrystals improve alopecia areata treatment by better targeting hair follicles.

In this case study, a 51-year-old Japanese man was diagnosed with desmoplastic trichoepithelioma after histological examination of surgically excised facial plaques.

This study reports the development of an artificial skin membrane incorporating hair follicles, intended as an in vitro model to better estimate drug permeation with less variability than current models used in transdermal drug delivery research.

This study evaluated a new high-power, 810 nm diode laser for hair removal, finding it to be effective and safe, with a mean hair reduction of 74.4% in one session, and noted it worked efficiently on both large and small areas with minimal side effects.

This work explores using a liquid crystalline phase to stabilize benzoyl peroxide nanosuspensions, suggesting a promising method to potentially reduce the side effects of acne treatments.

In this study, cubosome and hexosome carriers with antimicrobial peptides showed varied efficacy, with cubosomes protecting peptides from degradation and enhancing bactericidal effects in some cases, while hexosomes lacked antimicrobial activity.

This study found that the new HCC additive enhances the permeation of pigments and active ingredients into hair, suggesting potential use in developing functional cosmetic hair products.

In this study, the authors identified and characterized the Get3d protein, conserved across plants and photosynthetic bacteria, which localizes to the chloroplast in Arabidopsis thaliana and potentially plays a role in tail-anchored protein targeting, linked to photosynthesis homeostasis.

This study investigated the morphology and growth mechanisms of spherical crystal aggregates of minoxidil in various alcoholic solvents, finding that a n-butanol–ethyl acetate mixture produces unique spherulite aggregates with improved powder characteristics.

This study provides the first crystal structure of the human SRD5A2 enzyme, revealing key insights into its function and inhibition which may aid future drug development.

This study provided the crystal structure of the human steroid 5α-reductase 2 enzyme and identified key molecular mechanisms for testosterone reduction and finasteride inhibition, aiding in understanding disease-causing mutations and potentially facilitating new drug development.

This study presents the crystal structure of human SRD5A2 with finasteride and reveals insights into its enzyme catalysis and inhibition mechanisms, which may inform drug development.