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This study describes the molecular conformation and intermolecular interactions in the crystalline structure of the compound C24H31BrO4.

This study investigated the integration of crystal engineering and microneedle technology for androgenetic alopecia treatment, finding that microneedles loaded with newly developed Kopexil multicomponent crystals reduced drug diffusion rates in vitro compared to standard formulations.

This study comprehensively compared different crystalline forms of finasteride, including the new finasteride DMF solvate hemihydrate, to better understand their structural characteristics and intermolecular interactions.

This study found that single-crystal magnesium samples smaller than 100 nm exhibited increased plastic deformation due to greater activation of nonbasal planes as local flow stresses approached 2 GPa.

This study provided the first X-ray crystal structure of the mammalian steroid hormone reductase AKR1D1 and identified a disease-related mutant, P133R, which may impact bile acid metabolism and cause clinical symptoms.

This study explored the solubility and crystal structure of GI197111X, a 5-alpha reductase inhibitor for androgenetic alopecia, finding its solubility in Capmul MCM suitable for a soft gel dosage form.

This study determined the molecular structure of finasteride and its related crystalline forms, highlighting different hydrogen-bond interactions and structural configurations in various crystalline complexes.

In this study, two methotrexate-loaded liquid crystal formulations for topical application showed immunomodulatory effects and induced skin changes in mice with imiquimod-induced psoriasis.

Long-term use of canthaxanthin may cause reversible changes in the eye, including crystal deposits and altered vision responses.

This study determined that previous reports mistakenly identified different polymorphs of furosemide and finasteride, which are actually identical, due to incomplete data collection in single-crystal X-ray diffraction analysis.

This study found that applying botanical extracts improved the mechanical properties of bleached hair, reducing its permeability and increasing its crystalline content.

This review discusses the history, structure, and biological significance of keratins, including the crystal structure of a keratin helical segment, without reporting new experimental results.

In this study, researchers investigated the formation of spherical crystals of minoxidil in various alcoholic solvents, discovering new types like spherulite aggregates and a unique butterfly-shaped crystal, with the spherulite aggregates showing improved powder flow properties compared to other forms.

This case report describes a middle-aged man with chronic tophaceous gout who experienced a rare form of non-scarring alopecia due to urate crystal deposition around hair follicles, leading to hair loss that remarkably improved with targeted treatment including allopurinol and lifestyle changes.

This study found that laccase-assisted grafting of poly(tyrosine) onto wool materials improved shrinkage resistance and mechanical properties while causing minor decreases in crystallinity and thermal resistance, suggesting a potential "green" approach to enhance wool durability.

The book is a detailed guide on children's skin disorders, their causes, and diagnosis, with many images for medical professionals.

This study reports the synthesis and structural characterization of a novel dinuclear platinum(III) complex with potential antitumor and catalytic activity.

This study uncovered how Staphylococcus hominis transports an odor precursor molecule, potentially leading to new ways to control body odor production in humans.

This study reports that a specific transporter protein in Staphylococcus hominis is responsible for transporting a malodour precursor, thereby playing a key role in human body odor production.

This study reports that Ca 2+ binding alters the dynamics and surface properties of PKD-like domains in Clostridium histolyticum collagenases, enhancing their stability and potentially aiding in collagen-targeting vehicle development.

This chapter discusses phase transitions in various pharmaceutical examples and does not present any new research findings.

This study reports that carbamazepine can self-assemble into stable channel structures without guest polymers, while griseofulvin relies on guest molecules for structural stability in drug-polymer inclusion complexes.

This study found that the cytochrome P450 enzyme CYP-sb21 can hydroxylate cyclosporine A at multiple positions, reducing its immunosuppressive effects but retaining its hair growth-promoting side-effect, and suggests modifications to improve regioselectivity for commercial use.

5α-reductase inhibitors, like Finasteride and Dutasteride, help manage benign prostatic hyperplasia.

This article provides an overview of crystallization processes, challenges, and applications, discussing various techniques and examples, but it reports no new experimental findings.

This study found that finasteride competitively inhibits the enzyme AKR1D1 with low micromolar affinity but does not act as a mechanism-based inactivator.

In this study, researchers found that silica nanoparticles synthesized using cold plasma showed a higher biofilm inhibition effect on Staphylococcus aureus and Escherichia coli compared to those made with a magnetic stirrer.

The 15th-century Korean mummy's hair was well-preserved due to a protective lime-soil coating.

This model study describes how interactions between hair keratin and various materials alter hair's physical and mechanical properties by affecting noncovalent bonds.

This study found that hair follicle tissue effectively induced mineral formation in calcium phosphate solutions, likely due to its nucleating ability, which was lost when the tissue was lyophilized and stored.