Evaluation of Methotrexate-Loaded Surfactants, Ceramides, and Cholesterol-Based Lamellar Phases as a Topical Treatment for Psoriasis

    Cintia Oliveira Alves, Rômulo Dias Novaes, Maria Tereza Carneiro Paschoal Bernardes, Reggiani Vilela Gonçalves, Laíla Pereira da Silva, Sandra Barbosa Neder Agostini, Gislaine Ribeiro Pereira, Flávia Chiva Carvalho
    Studysummary In this study, two methotrexate-loaded liquid crystal formulations for topical application showed immunomodulatory effects and induced skin changes in mice with imiquimod-induced psoriasis.
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