Crystal Structure of Minoxidil

    January 2004 in “ Analytical Sciences X-ray Structure Analysis Online ”
    Hiroyuki Akama, Masayuki Haramura, Akito Tanaka, Toshio Akimoto, Noriaki Hirayama
    TLDR Minoxidil's crystal structure shows two different molecule shapes and nitrogen states.
    The study detailed the crystal structure of Minoxidil, an antialopecia agent, revealing that it belonged to the space group P21 with specific cell dimensions. The research found two crystallographically independent molecules in an asymmetric unit, which adopted significantly different conformations. Additionally, the nitrogen atoms in the piperidine rings exhibited markedly different hybridization states in these molecules.
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