Crystal Structure of Minoxidil
January 2004
in “
Analytical Sciences X-ray Structure Analysis Online
”
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Studysummary This structural study reports on the crystal properties of a compound used for treating alopecia, revealing different conformations and nitrogen hybridization in its piperidine rings.
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The study detailed the crystal structure of Minoxidil, an antialopecia agent, revealing that it belonged to the space group P21 with specific cell dimensions. The research found two crystallographically independent molecules in an asymmetric unit, which adopted significantly different conformations. Additionally, the nitrogen atoms in the piperidine rings exhibited markedly different hybridization states in these molecules.
