1 citations
,
June 2023 in “ScienceRise Pharmaceutical Science” This study explored a computer simulation method for selecting emulsion compositions in dermatology, finding that the PS biocomplex can be effectively used as an emulsifier or co-emulsifier, which streamlines the development process and reduces experimental demands.
January 2026 in “RIGGS Journal of Artificial Intelligence and Digital Business” This study evaluated formulations of a cream containing turmeric and ginger extracts for inhibiting underarm hair growth, finding that the formulation with 15% stearic acid and 3% triethanolamine had the most optimal physical characteristics and potential for cosmetic development.
2 citations
,
March 2019 in “Plastic and Reconstructive Surgery” This review discusses various mechanical isolation procedures for tissue-like stromal vascular fraction, such as the nanofat procedure, and highlights the need for controlled trials to assess their regenerative effectiveness.
13 citations
,
February 2018 in “Bio-medical Materials and Engineering” This study demonstrated that minoxidil-encapsulated PLLGA nanoparticles significantly increased minoxidil delivery to hair follicles compared to a minoxidil aqueous solution in mice.
3 citations
,
August 2025 in “Fermentation” In this study, researchers produced a biosurfactant from yeast that effectively reduces surface tension, acts as a good oil emulsifier, demonstrates antioxidant and antimicrobial properties, and exhibits no cytotoxicity, suggesting its potential use in eco-friendly cosmetic formulations.
2 citations
,
August 2021 in “Journal of pharmaceutical research international” This study concluded that fenugreek seed extract loaded solid lipid nanoparticles demonstrated enhanced skin retention and extended release, suggesting potential as a future alternative treatment for alopecia.
2 citations
,
September 2019 in “South Asian research journal of pharmaceutical sciences” This article reviews the risks of metal exposure from cosmetic products and emphasizes the need for stricter regulation and consumer awareness, without presenting new data or results.
5 citations
,
August 2025 in “Drug Delivery and Translational Research” This review discusses lipid-polymer hybrid nanoparticles for dermatological applications, outlining their structural and formulation advancements, but reports no new clinical results and calls for further research on their therapeutic potential.
September 2013 in “Daehan hwajangpum hakoeji/Daehan hwa'jangpum haghoeji” This study evaluated the effects of a shampoo containing ginsenoside Rg3 on hair loss prevention and regrowth, with no conclusive clinical results reported.
24 citations
,
October 2019 in “Biomaterials Research” This study investigated the use of Minoxidil encapsulated in HA-PLGA nanoparticles for alopecia treatment and found that these nanoparticles efficiently delivered the drug to hair follicle cells without significant cytotoxicity, offering a potential transdermal delivery method for various diseases.
December 2025 in “Advanced Healthcare Materials” This study introduces a spherical skin model that effectively mimics key features of human skin, offering a scalable and rapid alternative for non-animal dermatological and cosmetic testing.
September 2023 in “Pharmaceuticals” This study found that nanoparticles containing minoxidil and betamethasone improved drug delivery to hair follicles, with lipidic nanoparticles significantly enhancing minoxidil and betamethasone penetration compared to control, making them a promising option for alopecia areata treatment with reduced side effects.
September 2024 in “Journal of Cosmetic Dermatology” This study found that quercetin-loaded solid lipid nanoparticles demonstrated positive protective effects on human hair against UV-B light, as they controlled microscopic surface roughness, reduced chemical changes, and minimized protein loss in vitro compared to other treatments.
3 citations
,
October 2023 in “Cosmetics” This study developed effervescent cleansing tablets containing asiatic-acid-loaded solid lipid microparticles, finding that they provided effective cleansing compared to water and showed good flow properties, pH, and hardness but were unstable at high temperature and humidity.
9 citations
,
March 2022 in “Antioxidants” This review summarized and classified 32 approved synthetic and natural-identical antioxidants, examining their regulatory status, safety, pharmacological properties, and effectiveness on human health, aiming to clarify their antioxidant actions and encourage further research in the field.
December 2025 in “Sensors” In this review, recent advances in long-acting microneedle-based transdermal drug delivery systems are outlined, highlighting biodegradable polymers like PLA, PLGA, and PCL for sustained release and discussing challenges in clinical translation such as consistency in manufacturing and validating long-term efficacy and safety.
February 2021 in “International journal of regenerative medicine” In this study, emulsifying microfragmented adipose tissue increased the number of stromal vascular fraction cells available for regenerative treatments, suggesting the method's potential use in medical facilities.
6 citations
,
August 2021 in “International Journal of Pharmaceutics” This study demonstrated that finasteride-loaded PLGA microspheres created using a novel microfluidic device exhibit extended drug release in beagle dogs, with modifications allowing for release up to 3 months.
3 citations
,
October 2014 in “Pharmaceutical Development and Technology” This study found that an optimized microemulsion for minoxidil with high solubility, permeation flux, and skin deposition can be achieved with specific low and high levels of certain surfactants and co-solvents.
6 citations
,
March 2024 in “Saudi Pharmaceutical Journal” This study found that a nano-cubosome formulation co-loaded with capsaicin and thiocolchicoside enhanced bioavailability and showed promising analgesic and anti-inflammatory effects in rats, potentially benefiting gout management through improved transdermal delivery.
April 2025 in “Journal of Pharmaceutical Investigation” In this study, injectable microdepots containing rapamycin and poly(lactic-co-glycolic acid) were developed and demonstrated to effectively promote hair regrowth in mice by sustaining drug release and inducing anagen phase transition in hair follicles through modulating autophagy and the Wnt/β-catenin pathway.
25 citations
,
March 2024 in “Sustainability” This paper discusses strategies for creating sustainable cosmetic emulsions, highlighting the use of food waste, fermentation processes, and low-energy emulsification methods to minimize carbon footprint while preserving the bioactive properties of raw materials.
March 2011 in “Focus on surfactants” Several companies launched new hair care ingredients in 2011 to improve conditioning, color retention, combability, and heat protection.
356 citations
,
December 1986 in “The journal of cell biology/The Journal of cell biology” This study found that specific human hair keratins are differentially expressed in the hair follicle, suggesting a shared pathway of epithelial differentiation between hair cortex and nail plate cells.
148 citations
,
December 2018 in “Journal of autoimmunity” This review discusses genetic and environmental factors contributing to autoimmunity in alopecia areata and reports no new clinical findings, emphasizing the need for further study on its aetiology and pathophysiology.
This study focused on developing a nanoemulsion-based gel for delivering minoxidil, aiming to enhance its contact time with the scalp and potentially improve skin absorption compared to conventional topical solutions.
January 2026 in “International journal of research and scientific innovation” In this laboratory study, researchers developed a multifunctional organic hair cream with various natural extracts, finding that the cream with 15% extracts demonstrated higher physical stability, hair strength, and antimicrobial activity compared to lower concentration samples and synthetic alternatives.
41 citations
,
December 2008 in “Current Opinion in Ophthalmology” This review describes techniques to manage intraoperative floppy iris syndrome linked to alpha-1 blocker use in cataract surgery, highlighting the need for patient disclosure of medication use but reports no new clinical results.
January 2026 in “RIGGS Journal of Artificial Intelligence and Digital Business” This study analyzed the formulation and stability of pomade containing peppermint oil and minoxidil, determining that a particular formulation with 1% paraffin yielded optimal physical and stability characteristics for promoting hair growth, making it the best choice among the tested options.
February 2025 in “Processes” This study highlights the potential of chitosan nanoparticles to improve cannabidiol solubility and delivery for treating alopecia, suggesting a promising approach for transdermal delivery of hydrophobic compounds.