Modelling of the Composition of Emulsion Medicines and Cosmetics Stabilized by a Biocomplex of Surfactant Substances Based on Rhamnolipids Pseudomonas sp. PS-17
June 2023
in “
ScienceRise Pharmaceutical Science
”
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Studysummary This study explored a computer simulation method for selecting emulsion compositions in dermatology, finding that the PS biocomplex can be effectively used as an emulsifier or co-emulsifier, which streamlines the development process and reduces experimental demands.
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The study explores the use of a biocomplex of surfactants based on rhamnolipids Pseudomonas sp. PS-17 (biocomplex PS) as an emulsifier and co-emulsifier in dermatological emulsions. By employing computer simulation methods in the MO Excel program, the research aims to optimize the composition of oil phases and emulsifiers in medicinal and cosmetic emulsions, reducing the need for extensive experimental trials. The study demonstrates that a semi-automated modelling system can effectively guide the selection of emulsion components, either using the PS biocomplex alone or in combination with type II emulsifiers, thus streamlining the development process of emulsion products.
