Intraoperative Floppy Iris Syndrome: Management Strategies and Outcomes

    January 2009 in “ Current Opinion in Ophthalmology
    Salwa Hagag Abdelaziz, Nick Mamalis
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    TLDR Certain eye surgery complications can be managed effectively, especially in patients who have used specific prostate medications.
    The document from 2009 discusses Intraoperative Floppy Iris Syndrome (IFIS), a complication during cataract surgery linked to the use of systemic alpha-1 adrenergic receptor antagonists like tamsulosin. It outlines various management strategies for IFIS, such as preoperative atropine, intraoperative iris retractors, pupil expansion rings, viscoadaptive ophthalmic viscosurgical devices, and intracameral mydriatics. A multicenter study of 167 eyes in 135 patients showed a low incidence of posterior capsule rupture (0.6%) and a high success rate with 95% achieving at least 20/40 visual acuity. The document highlights the importance of recognizing the risk of IFIS in patients with a history of alpha-1 blocker use and the effectiveness of various management strategies when properly employed. It calls for patient and physician education on the risks associated with alpha-1 blockers and the necessity of ophthalmic evaluation before treatment, as well as further research to determine the most effective management of IFIS.
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