Spherical Skin Model: Stratified Co-Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening

Eye lens capsules are the best for growing human skin cells.

This study introduced a bioengineering platform that creates early-stage hair peg-like structures within tissue-engineered skin substitutes by integrating human keratinocytes and dermal papilla cells with laser-micropatterned collagen scaffolds, providing a foundation for future appendage-inclusive skin regeneration efforts.

This study found that dispersed hair follicle cells can be cultured successfully on collagen type IV, potentially offering an alternative to cultured epidermal keratinocytes for skin treatment.