November 2024 in “International Journal of Applied Pharmaceutics” This study found that a fenugreek seed extract nanoformulation significantly improved hair growth and length in Wistar rats with alopecia, outperforming conventional gels and oils, suggesting enhanced skin penetration and reduced side effects.
January 2025 in “RSC Advances” This study reported that a new formulation of finasteride solid lipid nanoparticles, combined with LPC and NTC, enhanced hair growth in mice without visible skin reactions, suggesting it could effectively manage androgenetic alopecia.
June 2026 in “Discover Nano” This review discusses current treatment strategies for alopecia and highlights the potential of lipid-based nanoparticles to improve drug delivery to the scalp and hair follicles, noting their ability to enhance skin penetration and drug stability while outlining associated challenges and the need for further research.
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July 2015 in “European journal of pharmaceutics and biopharmaceutics” This review discusses the application of lipid nanoparticles for enhancing drug delivery through hair follicles and reports no new clinical results, emphasizing the potential role of sebum-like lipids in this context.
July 2026 in “Journal of Drug Delivery and Therapeutics” This study evaluated Finasteride-loaded nanostructured lipid carriers for topical use in treating androgenetic alopecia and found that these carriers offer sustained drug release and may reduce systemic side effects compared to oral administration.