Optimization of Minoxidil Microemulsions Using Fractional Factorial Design Approach

    Napaphak Jaipakdee, Ekapol Limpongsa, Thaned Pongjanyakul
    Studysummary This study found that an optimized microemulsion for minoxidil with high solubility, permeation flux, and skin deposition can be achieved with specific low and high levels of certain surfactants and co-solvents.
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    Research cited in this study 5

    1. Transcutol-Containing Vesicles for Topical Delivery of Minoxidil Journal of Drug Targeting · 2010
    2. In Vitro Skin Permeation of Monoolein Nanoparticles Containing Hydroxypropyl β-Cyclodextrin/Minoxidil Complex International Journal of Pharmaceutics · 2010
    3. Formulation and In Vitro Assessment of Minoxidil Niosomes for Enhanced Skin Delivery International Journal of Pharmaceutics · 2009
    4. Evaluation of an Eucalyptus Oil Containing Topical Drug Delivery System for Selected Steroid Hormones International Journal of Pharmaceutics · 2006
    5. A Method for the Determination of Minoxidil in Hair-Regrowth Formulations by Micellar Electrokinetic Capillary Chromatography Farmaco · 2005

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    1. Optimization of Minoxidil Microemulsions Using Fractional Factorial Design Approach Pharmaceutical Development and Technology · 2014