Low-Dose Rapamycin Microdepots Promote Hair Regrowth via Autophagy Modulation

    April 2025 in “ Journal of Pharmaceutical Investigation ”
    Tiep Tien Nguyen, Trang N. Le, Ngọc Trần Nguyên … Jee‐Heon Jeong
    Studysummary In this study, injectable microdepots containing rapamycin and poly(lactic-co-glycolic acid) were developed and demonstrated to effectively promote hair regrowth in mice by sustaining drug release and inducing anagen phase transition in hair follicles through modulating autophagy and the Wnt/β-catenin pathway.
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    Research cited in this study 20

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