Evaluation of Anti-Hair Loss Shampoo Through In Vitro Activity in Human Hair Follicle Dermal Papilla Cells and Sensorial Study

    Camille Mas, Fabio Sanches, V. Mengeaud, Ana Coutinho, S. Bessou‐Touya, Fernanda Lopes da Silva Chaves, Hélène Duplan
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    TLDR The anti-hair loss shampoo effectively promotes hair growth and improves hair quality.
    The study evaluated an Anti-Hair Loss Shampoo containing a 6 active ingredient complex (Biotin, Hydrolyzed Wheat Protein, Dexpanthenol, Piridoxine, Tocopheryl Nicotinate, Ruscus Extract) for its effect on Wnt/β-catenin pathway activation in Human Hair Follicle Dermal Papilla Cells (HHFDPC) and its sensorial properties. The active complex significantly increased β-Catenin production by 192% compared to baseline, similar to Finasteride, promoting the anagen phase and hair growth. A sensorial study with 24 subjects showed the shampoo had excellent cleaning efficacy, volume, and shine, indicating good hair fiber quality improvement. The shampoo demonstrated essential attributes expected from an anti-hair loss product.
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