Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This article reviews in-vitro and cell-free methods for assessing the efficacy of herbal ingredients in cosmetic formulations for skin health and hair growth, but it reports no new clinical results.

This study found that RSPO1 mutations in patients with a 46XX disorder of sexual development contribute to impaired skin integrity and increased risk of squamous cell carcinoma in areas subject to friction.

In this study, Satura® Rosta remedy was found to significantly increase hair follicle size, hair root volume, and skin thickness in mice, potentially by prolonging the anagen phase, with notable hair regrowth observed in older mice with alopecia.

This study found that down-regulation of sonic hedgehog gene expression is a critical early event in chemotherapy-induced tissue damage in hair and feather follicles.

This study found that off-pump coronary surgery significantly reduces in-hospital morbidity compared to on-pump surgery without affecting midterm outcomes in the first 1-3 years after the procedure.

This study found that ectopic expression of Whn in transgenic mice caused impaired differentiation in epidermis and hair follicles, with hair growth defects and severe urinary tract issues leading to hydronephrosis.

This study found that human hair follicle dermal cells, specifically dermal sheath cells, can serve as an alternative and potentially superior cell source for constructing the dermal component of bioengineered skin in both in vitro and in vivo settings.

This study found that exposing adult esophageal epithelial cells to skin stroma can induce them to transition toward a hair follicle identity, with HIF1a playing a crucial role in this conversion process.

This study found that adipose-derived stem cells from adult guinea pigs can differentiate into hair cell-like cells in vitro, suggesting potential use in tissue engineering.

This study investigated the secretome of adipose mesenchymal stem cells and fibroblasts used in skin care products, finding 16 therapeutic pathways involving numerous signaling mechanisms, which may offer skin benefits through anti-inflammatory and regenerative effects.

This review discusses the cornification process of epidermal keratinocytes in forming the skin barrier and reports no new results; it emphasizes the importance for diagnosis and treatment of skin disorders.

This review discusses the potential applications and advantages of encapsulating single cells for use in therapeutics and diagnostics, while also evaluating various methods for effectively creating and sorting single-cell units despite challenges in production and cost.

This study demonstrates that mice with ectopic expression of the human GLI-1 gene in their skin developed tumors resembling human basal cell carcinoma, suggesting that GLI-1 is central to tumor development without additional p53 or Ha ras mutations.

In this study, researchers established that increased expression of the human GLI-1 gene in mouse skin leads to the development of tumors that closely resemble human basal cell carcinomas, without requiring additional mutations in the p53 or Ha ras genes.

This article reviews the complex signaling pathways between epithelial and mesenchymal cells crucial for hair follicle morphogenesis, highlighting the Wnt pathway's role as a master regulator without reporting new experimental findings.

This research discusses how epithelial stem cells in the skin maintain normal homeostasis, contribute to wound repair, and highlights the importance of these processes, as defects can lead to skin diseases including cancers, but provides no new experimental results.

This review summarizes current knowledge on tight junctions in mammalian skin and their role in drug delivery and interaction with other barrier components, but reports no new experimental results.

This review discusses various nanoparticles and nanoemulsions being investigated for transdermal drug delivery and reports no clinical results; it highlights potential applications in treating alopecia, wound healing, psoriasis, and melanoma.

This review explores the mechanisms of adult stem cell self-renewal, using skin as a model, and reports no new results but raises important unanswered questions in the field.

This essay discusses the establishment, maintenance, and role of skin stem cells in tissue homeostasis, wound repair, and their relation to skin cancer, without reporting new experimental findings.

This review explores the role of Foxn1 in mammalian skin biology, discussing its influence on hair follicle function and the potential for further research to enhance understanding of epithelial differentiation.

This article reviews recent advancements in understanding skin stem cells and their roles in maintaining epidermal homeostasis and repairing wounds, without presenting new experimental findings.

This review discusses current experimental approaches for regenerating human hair follicles using tissue engineering and isolated cells, but reports no successful strategies with adult cells yet found.

This research abstract provides no results, focusing on the equal contributions of the authors in the field of molecular, cellular, and developmental biology from Yale University.

This paper argues that the cycling hair follicle serves as a valuable model for systems biology research, highlighting its potential for translational medicine.

This study identified hair shaft progenitors in the matrix that regulate hair growth and pigmentation by creating a niche dependent on stem cell factor, implicating KROX20+ cells in these processes.

This review discusses the effects of thyroid hormone on the skin and explores the potential for using it to treat skin diseases, but reports no new clinical results.

This study found that horizontal sections of scalp biopsies in patients with Central Centrifugal Cicatricial Alopecia often reveal follicular miniaturization, inflammation, and scarring, which can guide personalized treatment.

This review explores the role of fatty acids and bioactive lipid mediators in skin health and suggests targeting this metabolic network to control inflammation and improve skin conditions, but it reports no new findings.

This study observed that Endoglin is crucial for maintaining correct hair follicle cycling and stimulating hair follicle stem cell niches through feedback interactions involving Wnt/β-catenin and Bmp/Smad signaling pathways in a mouse model.