Unveiling the Potential of Single-Cell Encapsulation in Biomedical Applications: Current Advances and Future Perspectives

Single-cell encapsulation is a promising technique in biomedical applications, offering precise control over cellular environments for regenerative medicine, drug delivery, and cellular studies. It enables high-throughput screening, improved cell viability, and reduced immune rejection, with applications in T-cell therapies, tissue engineering, and hair loss treatment. Techniques like droplet microfluidics, hydrogel-based methods, and nanoencapsulation each present unique benefits and challenges, such as stability and nutrient exchange issues. Despite the absence of licensed products due to production challenges, advancements in sorting strategies and encapsulation technologies hold potential for revolutionizing personalized medicine and regenerative therapies.