Microencapsulated Hair Follicle Dermal Papilla Cell with Hyaluronic Acid/Collagen Hydrogel

In the 2020 study, researchers focused on the role of dermal papilla (DP) cells in hair growth and their potential in treating alopecia. They encapsulated DP cells within a hyaluronic acid/collagen (HA/Col) hydrogel to create microcapsules. These microcapsules were then characterized using physicochemical analysis and scanning electron microscopy, which confirmed their uniform, micro-sized spherical shape. The viability and follicle-inducing capability of the encapsulated DP cells were assessed through colorimetric assays and immunofluorescence. The study concluded that the microencapsulated DP cells maintained their ability to initiate hair follicle regeneration, suggesting that this method could be used for cell therapy in alopecia treatment and skin tissue engineering.