Reconstruction of Hair Follicle-Like Structure with Hair Follicle Cells on Collagen/Chitosan Porous Scaffolds

January 2006 in “ Chinese Journal of Dermatology ”

Min Zheng

hair follicle cells collagen chitosan porous scaffolds in vitro reconstruction hair follicle-like structures

TLDR Hair follicle-like structures can be created using hair cells on collagen/chitosan scaffolds.

The study investigated the potential for in vitro reconstruction of hair follicles by implanting hair follicle cells onto collagen/chitosan porous scaffolds. Hair follicle cells from 4-day old C57BL/6 mice were cultured and implanted into the scaffolds at varying densities and passages. Observations using microscopy techniques revealed that hair follicle-like structures with hair stems could form within the scaffolds when cells were implanted at specific densities and passages. The conclusion was that hair follicle-like structures could be generated from collagen/chitosan porous scaffolds implanted with hair follicle cells in vitro.

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